Anti-Sex Hormone Binding Globulin/SHBG antibody [SPM605] - BSA and Azide free (ab212827)

Overview

  • Product name

    Anti-Sex Hormone Binding Globulin/SHBG antibody [SPM605] - BSA and Azide free
    See all Sex Hormone Binding Globulin/SHBG primary antibodies
  • Description

    Mouse monoclonal [SPM605] to Sex Hormone Binding Globulin/SHBG - BSA and Azide free
  • Host species

    Mouse
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant full length protein corresponding to Human Sex Hormone Binding Globulin/SHBG.
    Database link: P04278

  • Positive control

    • IHC-P: Human testicular carcinoma tissue.
  • General notes

    Previously labelled as Sex Hormone Binding Globulin. 

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Constituent: PBS
  • Concentration information loading...
  • Purity

    Protein A/G purified
  • Purification notes

    ab212827 was purified from bioreactor concentrate by protein A/G.
  • Clonality

    Monoclonal
  • Clone number

    SPM605
  • Isotype

    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab212827 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 1 - 2 µg/ml. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

(Primary incubation for 30 minutes at RT).

Target

  • Function

    Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration.
  • Tissue specificity

    Isoform 1 and isoform 2 are present in liver and testis.
  • Sequence similarities

    Contains 2 laminin G-like domains.
  • Cellular localization

    Secreted. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.
  • Information by UniProt
  • Database links

  • Alternative names

    • ABP antibody
    • Androgen binding protein antibody
    • SBP antibody
    • Sex hormone-binding globulin antibody
    • Sex steroid binding protein antibody
    • Sex steroid-binding protein antibody
    • SHBG antibody
    • SHBG_HUMAN antibody
    • TeBG antibody
    • Testis specific androgen binding protein antibody
    • Testis-specific androgen-binding protein antibody
    • Testosterone binding beta globulin antibody
    • Testosterone estradiol binding globulin antibody
    • Testosterone estrogen binding globulin antibody
    • Testosterone-estradiol-binding globulin antibody
    • Testosterone-estrogen-binding globulin antibody
    see all

Images

  • Formalin-fixed, paraffin-embedded human testicular carcinoma tissue stained for Sex Hormone Binding Globulin/SHBG using ab212827 at 2 µg/ml in immunohistochemical analysis.

    This IHC-P data was generated using the same anti-Sex Hormone Binding Globulin/SHBG antibody clone, SPM605, in a different buffer formulation.

References

ab212827 has not yet been referenced specifically in any publications.

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