Overview

  • Product name

  • Description

    Rabbit polyclonal to Sez6
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within the C terminal amino acids 826-875 (RAPKCLLEQL KPCHGLSAPE NGARSPEKQL HPAGATIHFS CAPGYVLKGQ) of the Human Sez6 protein (NP_849191).

  • Positive control

    • PANC1 cell lysate

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab135406 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 107 kDa.

Target

  • Function

    May play a role in cell-cell recognition and in neuronal membrane signaling. Seems to be important for the achievement of the necessary balance between dendrite elongation and branching during the elaboration of a complex dendritic arbor. Involved in the development of appropriate excitatory synaptic connectivity.
  • Sequence similarities

    Belongs to the SEZ6 family.
    Contains 2 CUB domains.
    Contains 5 Sushi (CCP/SCR) domains.
  • Post-translational
    modifications

    Glycosylated.
  • Cellular localization

    Cell membrane. Localized on dendrites and in the synaptic and postsynaptic fraction.
  • Information by UniProt
  • Database links

  • Alternative names

    • Brain-specific receptor-like protein C antibody
    • BSRP-C antibody
    • hSEZ-6 antibody
    • Seizure protein 6 antibody
    • Seizure protein 6 homolog antibody
    • Seizure related gene 6 antibody
    • SEZ-6 antibody
    • Sez6 antibody
    • SEZ6_HUMAN antibody
    see all

Images

  • Anti-Sez6 antibody (ab135406) at 1 µg/ml + PANC1 cell lysate at 10 µg

    Predicted band size: 107 kDa



    Blocking with 5% milk.

References

ab135406 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Abreviews
Application
Western blot
Sample
Mouse Tissue lysate - whole (spinal cord)
Gel Running Conditions
Reduced Denaturing (4-12%)
Loading amount
25 µg
Specification
spinal cord
Blocking step
Milk as blocking agent for 3 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: RT°C

Abcam user community

Verified customer

Submitted Jan 17 2017

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