Anti-SFRP2 antibody (ab77618)

Submit a review Q&A (1)References (2)

Overview

  • Product name

    Anti-SFRP2 antibody
    See all SFRP2 primary antibodies

  • Description

    Goat polyclonal to SFRP2

  • Host species

    Goat

  • Tested applications

    Suitable for: WBmore details

  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Chicken, Cow, Dog, Chimpanzee, Zebrafish

  • Immunogen

    Synthetic peptide:

    C-KRWQKGQREFKR

    , corresponding to C terminal amino acids 274-285 of Human SFRP2 (NP_003004.1)

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • Positive control

    • Human Duodenum lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab77618 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 33 kDa).

Target

  • Function

    Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis.

  • Tissue specificity

    Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon.

  • Sequence similarities

    Belongs to the secreted frizzled-related protein (sFRP) family.
    Contains 1 FZ (frizzled) domain.
    Contains 1 NTR domain.

  • Domain

    The FZ domain is involved in binding with Wnt ligands.

  • Cellular localization

    Secreted.
  • Information by UniProt

  • Database links

    see all

  • Alternative names

    • AI851596 antibody
    • Frizzled related protein 2 antibody
    • FRP 2 antibody
    • FRP-2 antibody
    • FRP2 antibody
    • MGC128911 antibody
    • MGC153618 antibody
    • MGC53344 antibody
    • SARP 1 antibody
    • SARP-1 antibody
    • SARP1 antibody
    • SDF 5 antibody
    • SDF5 antibody
    • Secreted apoptosis related protein 1 antibody
    • Secreted apoptosis-related protein 1 antibody
    • Secreted frizzled related protein 2 antibody
    • Secreted frizzled-related protein 2 antibody
    • sFRP 2 antibody
    • sFRP-2 antibody
    • SFRP2 antibody
    • Sfrp2 protein antibody
    • SFRP2_HUMAN antibody
    see all

Images

References

This product has been referenced in:

  • Peterson YK  et al. Frizzled-5: a high affinity receptor for secreted frizzled-related protein-2 activation of nuclear factor of activated T-cells c3 signaling to promote angiogenesis. Angiogenesis 20:615-628 (2017). Read more (PubMed: 28840375) »
  • Yamamura S  et al. Oncogenic functions of secreted Frizzled-related protein 2 in human renal cancer. Mol Cancer Ther 9:1680-7 (2010). WB ; Human . Read more (PubMed: 20501806) »
See all 2 Publications for this product

Publishing research using ab77618? Please let us know so that we can cite the reference in this datasheet.

Customer reviews and Q&As

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Submit a question

Question

I have been using your sFRP2 antibody (ab77618)for western blots and I would now like to try it in an Elisa. Could you recommend an appropriate secondary for this please? Thank you.

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Answer

Thank you for contacting us.

I have conducted a search in our catalogue for secondaries against ab77618 and found a wide range that could fit your requirements.

Depending on the conjugation and the species they are raised in, you can narrow the search.

Please have a look at the https://www.abcam.com/index.html?pageconfig=searchresults&search=IgG&pt=7&sk=targ&sv=IgG&sn=IgG&l=3&fViewMore=1, and if you had specific questions about the products identified during the search, please do not hesitate to contact me.

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