Anti-SFRS7/SRSF7 antibody (ab138022)

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Overview

  • Product name

    Anti-SFRS7/SRSF7 antibody
    See all SFRS7/SRSF7 primary antibodies

  • Description

    Rabbit polyclonal to SFRS7/SRSF7

  • Host species

    Rabbit

  • Tested applications

    Suitable for: WBmore details

  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse

  • Immunogen

    Synthetic peptide corresponding to Human SFRS7/SRSF7 (internal sequence).

  • Positive control

    • HT29 cell lysate

  • General notes

     This product was previously labelled as SFRS7

     

Properties

Applications

Our Abpromise guarantee covers the use of ab138022 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 27 kDa.

Target

  • Function

    Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10.

  • Tissue specificity

    Brain, liver, kidney and lung.

  • Sequence similarities

    Belongs to the splicing factor SR family.
    Contains 1 CCHC-type zinc finger.
    Contains 1 RRM (RNA recognition motif) domain.

  • Post-translational
    modifications

    Extensively phosphorylated on serine residues in the RS domain.

  • Cellular localization

    Nucleus.
  • Information by UniProt

  • Database links

    • Alternative names

      • 9G8 antibody
      • AAG3 antibody
      • arginine/serine-rich 7 antibody
      • HSSG1 antibody
      • RBM37 antibody
      • Serine/arginine-rich splicing factor 7 antibody
      • Splicing factor 9G8 antibody
      • Splicing factor antibody
      • Splicing factor, arginine/serine rich 7 antibody
      • SRSF7 antibody
      • SRSF7_HUMAN antibody
      • ZCCHC20 antibody
      • ZCRB2 antibody
      see all

    Images

    • Western blot - Anti-SFRS7/SRSF7 antibody (ab138022)
      Western blot - Anti-SFRS7/SRSF7 antibody (ab138022)
      Anti-SFRS7/SRSF7 antibody (ab138022) at 1/500 dilution + HT29 cell lysate at 30 µg

      Predicted band size: 27 kDa

    References

    This product has been referenced in:

    • Llorian M  et al. The alternative splicing program of differentiated smooth muscle cells involves concerted non-productive splicing of post-transcriptional regulators. Nucleic Acids Res 44:8933-8950 (2016). WB ; Mouse . Read more (PubMed: 27317697) »
    See 1 Publication for this product

    Publishing research using ab138022? Please let us know so that we can cite the reference in this datasheet.

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