Anti-SFRS7/SRSF7 antibody (ab138022)
Key features and details
- Rabbit polyclonal to SFRS7/SRSF7
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-SFRS7/SRSF7 antibody
See all SFRS7/SRSF7 primary antibodies -
Description
Rabbit polyclonal to SFRS7/SRSF7 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse -
Immunogen
Synthetic peptide corresponding to Human SFRS7/SRSF7 (internal sequence).
-
Positive control
- HT29 cell lysate
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride
PBS without Mg2+ and Ca2+ -
Concentration information loading...
-
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab138022 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/500 - 1/1000. Predicted molecular weight: 27 kDa.
|
Notes |
---|
WB
1/500 - 1/1000. Predicted molecular weight: 27 kDa. |
Target
-
Function
Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. -
Tissue specificity
Brain, liver, kidney and lung. -
Sequence similarities
Belongs to the splicing factor SR family.
Contains 1 CCHC-type zinc finger.
Contains 1 RRM (RNA recognition motif) domain. -
Post-translational
modificationsExtensively phosphorylated on serine residues in the RS domain. -
Cellular localization
Nucleus. - Information by UniProt
-
Database links
- Entrez Gene: 6432 Human
- Entrez Gene: 225027 Mouse
- Omim: 600572 Human
- SwissProt: Q16629 Human
- SwissProt: Q8BL97 Mouse
- Unigene: 309090 Human
- Unigene: 292016 Mouse
-
Alternative names
- 9G8 antibody
- AAG3 antibody
- arginine/serine-rich 7 antibody
see all
Images
Datasheets and documents
-
SDS download
-
Datasheet download
References (3)
ab138022 has been referenced in 3 publications.
- Kazuma Y et al. ILF2 enhances the DNA cytosine deaminase activity of tumor mutator APOBEC3B in multiple myeloma cells. Sci Rep 12:2278 (2022). PubMed: 35145187
- Tang SJ et al. Cis- and trans-regulations of pre-mRNA splicing by RNA editing enzymes influence cancer development. Nat Commun 11:799 (2020). PubMed: 32034135
- Llorian M et al. The alternative splicing program of differentiated smooth muscle cells involves concerted non-productive splicing of post-transcriptional regulators. Nucleic Acids Res 44:8933-8950 (2016). WB ; Mouse . PubMed: 27317697