Overview

  • Product name
  • Description
    Rabbit polyclonal to SFRS9
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Pig
  • Immunogen

    Recombinant fragment corresponding to a region within amino acids 52-199 of Human SFRS9 (Uniprot: Q13242).

  • Positive control
    • 293T, A431, H1299, MOLT4 and Raji whole cell lysates.
  • General notes
    Keep as concentrated solution.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 89% PBS, 10% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab155484 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 26 kDa.

Target

  • Function
    Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10.
  • Tissue specificity
    Expressed at high levels in the heart, kidney, pancreas and placenta, and at lower levels in the brain, liver, lung and skeletal muscle.
  • Sequence similarities
    Belongs to the splicing factor SR family.
    Contains 2 RRM (RNA recognition motif) domains.
  • Post-translational
    modifications
    Extensively phosphorylated on serine residues in the RS domain.
  • Cellular localization
    Nucleus. Cellular stresses such as heat shock may induce localization to discrete nuclear bodies termed SAM68 nuclear bodies (SNBs), HAP bodies, or stress bodies. Numerous splicing factors including SRSF1/SFRS1/SF2, SRSF7/SFRS7, SAFB and KHDRBS1/SAM68 accumulate at these structures, which may participate in the post-transcriptional regulation of mRNAs in stressed cells.
  • Information by UniProt
  • Database links
  • Alternative names
    • arginine/serine-rich 9 antibody
    • Pre mRNA splicing factor SRp30C antibody
    • Pre-mRNA-splicing factor SRp30C antibody
    • Serine/arginine-rich splicing factor 9 antibody
    • SFRS 9 antibody
    • Splicing factor antibody
    • Splicing factor arginine/serine rich 9 antibody
    • splicing factor, arginine/serine-rich 9 antibody
    • splicing factor, arginine/serine-rich, 30-KD, C antibody
    • SR splicing factor 9 antibody
    • SRP30C antibody
    • SRSF9 antibody
    • SRSF9_HUMAN antibody
    see all

Images

  • All lanes : Anti-SFRS9 antibody (ab155484) at 1/500 dilution

    Lane 1 : 293T whole cell lysate
    Lane 2 : MOLT4 whole cell lysate
    Lane 3 : Raji whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 26 kDa



    12% SDS PAGE

References

This product has been referenced in:
See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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