Key features and details
- Suitable for: Blocking
Product nameSGLT1 peptide
See all SGLT1 proteins and peptides
Our Abpromise guarantee covers the use of ab190911 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C long term.
- High affinity sodium glucose cotransporter
- High affinity sodium glucose cotransporter 1
FunctionActively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules.
Tissue specificityExpressed mainly in intestine and kidney.
Involvement in diseaseCongenital glucose/galactose malabsorption
Sequence similaritiesBelongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
modificationsN-glycosylation is not necessary for the cotransporter function.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab190911 has been referenced in 2 publications.
- Klinger S et al. Degree of SGLT1 phosphorylation is associated with but does not determine segment-specific glucose transport features in the porcine small intestines. Physiol Rep 6:N/A (2018). PubMed: 29333720
- Jensen VFH et al. Chronic Hyperinsulinaemic Hypoglycaemia in Rats Is Accompanied by Increased Body Weight, Hyperleptinaemia, and Decreased Neuronal Glucose Transporter Levels in the Brain. Int J Endocrinol 2017:7861236 (2017). PubMed: 28421113