SGLT1 peptide (ab190911)
Key features and details
- Suitable for: Blocking
Description
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Product name
SGLT1 peptide
See all SGLT1 proteins and peptides -
Animal free
No -
Nature
Synthetic
Associated products
-
Corresponding Antibody
Specifications
Our Abpromise guarantee covers the use of ab190911 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at -20°C long term.
General Info
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Alternative names
- D22S675
- High affinity sodium glucose cotransporter
- High affinity sodium glucose cotransporter 1
see all -
Function
Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules. -
Tissue specificity
Expressed mainly in intestine and kidney. -
Involvement in disease
Congenital glucose/galactose malabsorption -
Sequence similarities
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. -
Post-translational
modificationsN-glycosylation is not necessary for the cotransporter function. -
Cellular localization
Membrane. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (2)
ab190911 has been referenced in 2 publications.
- Klinger S et al. Degree of SGLT1 phosphorylation is associated with but does not determine segment-specific glucose transport features in the porcine small intestines. Physiol Rep 6:N/A (2018). PubMed: 29333720
- Jensen VFH et al. Chronic Hyperinsulinaemic Hypoglycaemia in Rats Is Accompanied by Increased Body Weight, Hyperleptinaemia, and Decreased Neuronal Glucose Transporter Levels in the Brain. Int J Endocrinol 2017:7861236 (2017). PubMed: 28421113
