SGLT1 peptide (ab190911)

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Key features and details

  • Suitable for: Blocking

Description

  • Product name

    SGLT1 peptide

  • Animal free

    No

  • Nature

    Synthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab190911 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-SGLT1 antibody (ab14686)

  • Form

    Liquid

  • Additional notes

    This product is a blocking peptide for ab14686.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C long term.

General Info

  • Alternative names

    • D22S675
    • High affinity sodium glucose cotransporter
    • High affinity sodium glucose cotransporter 1
    • High affinity sodium-glucose cotransporter
    • Human Na+/glucose cotransporter 1
    • Na(+)/glucose cotransporter 1
    • Na+/glucose cotransporter 1
    • NAGT
    • SC5A1_HUMAN
    • SGLT 1
    • SGLT1
    • SLC5A1
    • Sodium glucose cotransporter 1
    • Sodium/glucose cotransporter 1
    • Solute carrier family 5 (sodium/glucose cotransporter) member 1
    • Solute carrier family 5 member 1
    see all

  • Function

    Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules.

  • Tissue specificity

    Expressed mainly in intestine and kidney.

  • Involvement in disease

    Congenital glucose/galactose malabsorption

  • Sequence similarities

    Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.

  • Post-translational
    modifications

    N-glycosylation is not necessary for the cotransporter function.

  • Cellular localization

    Membrane.
  • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (2)

Publishing research using ab190911? Please let us know so that we can cite the reference in this datasheet.

ab190911 has been referenced in 2 publications.

  • Klinger S  et al. Degree of SGLT1 phosphorylation is associated with but does not determine segment-specific glucose transport features in the porcine small intestines. Physiol Rep 6:N/A (2018). PubMed: 29333720
  • Jensen VFH  et al. Chronic Hyperinsulinaemic Hypoglycaemia in Rats Is Accompanied by Increased Body Weight, Hyperleptinaemia, and Decreased Neuronal Glucose Transporter Levels in the Brain. Int J Endocrinol 2017:7861236 (2017). PubMed: 28421113

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