Overview

  • Product name

    Anti-SGPL1 antibody - C-terminal
    See all SGPL1 primary antibodies
  • Description

    Rabbit polyclonal to SGPL1 - C-terminal
  • Host species

    Rabbit
  • Specificity

    ab198804 detects endogenous levels of total SGPL1 protein.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human SGPL1 (C terminal). NP_003892. (Residues near the C terminus).
    Database link: O95470

  • Positive control

    • Human brain tissue and Human breast cancer tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab198804 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/25 - 1/100.

Target

  • Function

    Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis.
  • Tissue specificity

    Found in liver and kidney.
  • Pathway

    Lipid metabolism; sphingolipid metabolism.
  • Sequence similarities

    Belongs to the group II decarboxylase family. Sphingosine-1-phosphate lyase subfamily.
  • Cellular localization

    Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • FLJ13811 antibody
    • hSPL antibody
    • KIAA1252 antibody
    • S1P antibody
    • S1PL antibody
    • SGPL 1 antibody
    • SGPL1 antibody
    • SGPL1_HUMAN antibody
    • SP lyase antibody
    • SP-lyase 1 antibody
    • Sphingosine 1 phosphate aldolase antibody
    • Sphingosine 1 phosphate lyase 1 antibody
    • Sphingosine-1-phosphate aldolase antibody
    • Sphingosine-1-phosphate lyase 1 antibody
    • SPL 1 antibody
    • SPL antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human brain tissue labeling SGPL1 with ab198804 at 1/25 dilution.

  • Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue labeling SGPL1 with ab198804 at 1/25 dilution.

References

ab198804 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab198804.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up