Overview

  • Product name

    SH-5, Akt inhibitor
  • Description

    Specific Akt inhibitor
  • Biological description

    Specific Akt inhibitor. Synthetic phosphatidyl inositol. Has no effect on other downstream kinases. Potent inducer of apoptosis. Cell-permeable.
  • Purity

    > 98%
  • CAS Number

    701976-54-7
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Krech T  et al. Characterization of AKT independent effects of the synthetic AKT inhibitors SH-5 and SH-6 using an integrated approach combining transcriptomic profiling and signaling pathway perturbations. BMC Cancer 10:287 (2010). Read more (PubMed: 20546605) »
  • Gills JJ  et al. Phosphatidylinositol ether lipid analogues that inhibit AKT also independently activate the stress kinase, p38alpha, through MKK3/6-independent and -dependent mechanisms. J Biol Chem 282:27020-9 (2007). Read more (PubMed: 17631503) »
See 1 Publication for this product

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