Anti-SH2D4A antibody - N-terminal (ab170797)

Overview

  • Product name
    Anti-SH2D4A antibody - N-terminal
    See all SH2D4A primary antibodies
  • Description
    Rabbit polyclonal to SH2D4A - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human SH2D4A aa 45-75 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q9H788

  • Positive control
    • NCI-H292 cell line lysates. Human kidney tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab170797 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 53 kDa.
IHC-P 1/10 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.
  • Tissue specificity
    Ubiquitously expressed. Aberrantly expressed in some cancers.
  • Sequence similarities
    Contains 1 SH2 domain.
  • Cellular localization
    Cytoplasm. Located at podocyte foot processes.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ20967 antibody
    • PPP1R38 antibody
    • Protein phosphatase 1 regulatory subunit 38 antibody
    • Protein SH antibody
    • Protein SH(2)A antibody
    • Protein SH2A antibody
    • SH2 domain containing 4A antibody
    • SH2 domain containing protein 4A antibody
    • SH2 domain-containing protein 4A antibody
    • SH24A_HUMAN antibody
    • SH2A antibody
    • Sh2d4a antibody
    see all

Images

  • Immunohistochemical analysis of Formalin/PFA-fixed paraffin-embedded Human kidney tissue labeling SH2D4A with ab170797 at a 1/10 dilution followed by peroxidase conjugation of the secondary antibody and DAB staining.

  • Anti-SH2D4A antibody - N-terminal (ab170797) at 1/100 dilution + NCI-H292 cell line lysates at 35 µg

    Predicted band size: 53 kDa

References

ab170797 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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