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Chicken polyclonal to SH3 containing Grb 2 like 1 protein - Azide free
This antibody is specific for SH3 containing Grb 2 like 1 protein.
Mouse, Rat, Human
Synthetic peptide, corresponding to amino acids 1-360 of SH3 containing Grb 2 like 1 protein.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
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Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||1/2000. Predicted molecular weight: 41 kDa.
Implicated in endocytosis. May recruit other proteins to membranes with high curvature.
Ubiquitous. Higher expression in pancreas, placenta, prostate, testis and uterus.
Involvement in disease
Note=In some cases of acute leukemia, a translocation results in the formation of a MLL-EEN fusion gene.
Belongs to the endophilin family.
Contains 1 BAR domain.
Contains 1 SH3 domain.
An N-terminal amphipathic helix, the BAR domain and a second amphipathic helix inserted into helix 1 of the BAR domain (N-BAR domain) induce membrane curvature and bind curved membranes.
Cytoplasm. Early endosome membrane. Associated with postsynaptic endosomes in hippocampal neurons.
Information by UniProt
- CNSA1 antibody
- EEN antibody
- EEN fusion partner of MLL antibody
Western blot - Anti-SH3 containing Grb 2 like 1 protein antibody - Azide free (ab37656)
Anti-SH3 containing Grb 2 like 1 protein antibody - Azide free (ab37656) at 1/2000 dilutionSecondary
Goat anti-IgY-HRP. at 1/1000 dilutionPredicted band size:
41 kDaObserved band size:
100 kDa (why is the actual band size different from the predicted?
E coli-derived fusion protein as test antigen.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"