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Cell Biology Other Antibodies Oxidative Stress
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Anti-SH3BGRL3 antibody (ab122138)

  • Datasheet
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Western blot - Anti-SH3BGRL3 antibody (ab122138)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SH3BGRL3 antibody (ab122138)
  • Immunocytochemistry/ Immunofluorescence - Anti-SH3BGRL3 antibody (ab122138)

Key features and details

  • Rabbit polyclonal to SH3BGRL3
  • Suitable for: IHC-P, WB, ICC/IF
  • Reacts with: Human
  • Isotype: IgG

You may also be interested in

Protein
Product image
Recombinant Human SH3BGRL3 protein (ab134546)
Secondary
Product image
Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

View more associated products

Overview

  • Product name

    Anti-SH3BGRL3 antibody
  • Description

    Rabbit polyclonal to SH3BGRL3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    antigen sequence: SEVTRILDGK RIQYQLVDIS QDNALRDEMR ALAGNPKATP PQIVNGDQYC GDYELFVEAV EQNTLQEFLK LA, corresponding to amino acids 22-93 of Human SH3BGRL3

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • Positive control

    • Human smooth muscle tissue; RT4 cell lysates and Human liver and tonsil tissue lysates; U2OS cells
  • General notes

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Cell Biology
    • Other Antibodies
    • Oxidative Stress

Associated products

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
  • Recombinant Protein

    • Recombinant Human SH3BGRL3 protein (ab134546)

Applications

Our Abpromise guarantee covers the use of ab122138 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/600. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB Use a concentration of 0.04 - 0.4 µg/ml.
ICC/IF Use a concentration of 1 - 4 µg/ml. Fixed/permeabilized with PFA/Triton X-100

Target

  • Function

    Could act as a modulator of glutaredoxin biological activity.
  • Tissue specificity

    Ubiquitous.
  • Sequence similarities

    Belongs to the SH3BGR family.
    Contains 1 glutaredoxin domain.
  • Cellular localization

    Cytoplasm. Nucleus.
  • Target information above from: UniProt accession Q9H299 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 83442 Human
    • SwissProt: Q9H299 Human
    • Unigene: 109051 Human
    • Alternative names

      • epididymis secretory protein Li 297 antibody
      • HEL-S-297 antibody
      • SH3 domain binding glutamic acid rich protein like 3 antibody
      • SH3 domain-binding glutamic acid-rich-like protein 3 antibody
      • SH3 domain-binding protein 1 antibody
      • Sh3bgrl3 antibody
      • SH3BGRL3 like protein antibody
      • SH3BP-1 antibody
      • SH3L3_HUMAN antibody
      • TIP B1 antibody
      • TIP-B1 antibody
      • TNF inhibitory protein antibody
      see all

    Images

    • Western blot - Anti-SH3BGRL3 antibody (ab122138)
      Western blot - Anti-SH3BGRL3 antibody (ab122138)
      All lanes : Anti-SH3BGRL3 antibody (ab122138) at 1/250 dilution

      Lane 1 : RT4 cell lysates
      Lane 2 : U251MG cell lysates
      Lane 3 : Human plasma
      Lane 4 : Human liver tissue lysate
      Lane 5 : Human tonsil tissue lysate
    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SH3BGRL3 antibody (ab122138)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SH3BGRL3 antibody (ab122138)
      ab122138, at 1/600 dilution, staining SH3BGRL3 in Human smooth muscle tissue by Immunohistochemistry using paraffin-embedded tissue.
    • Immunocytochemistry/ Immunofluorescence - Anti-SH3BGRL3 antibody (ab122138)
      Immunocytochemistry/ Immunofluorescence - Anti-SH3BGRL3 antibody (ab122138)
      ab122138 at 4 µg/ml staining SH3BGRL3 in PFA/Triton X-100 fixed/permeabilized U2OS cells by Immunofluorescence. Antibody staining is shown in green

    Protocols

    • Immunohistochemistry protocols
    • Immunocytochemistry & immunofluorescence protocols
    • Western blot protocols

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab122138? Please let us know so that we can cite the reference in this datasheet.

    ab122138 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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