Overview

  • Product name

    Anti-SH3GL2 antibody (Biotin)
    See all SH3GL2 primary antibodies
  • Description

    Goat polyclonal to SH3GL2 (Biotin)
  • Host species

    Goat
  • Conjugation

    Biotin
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to Human SH3GL2 aa 262-274 (internal sequence) (Cysteine residue). NP_003017.1
    Sequence:

    C-SLEFPTGDSTQPN


    Database link: Q99962

  • Positive control

    • WB: Human frontal cortex lysate.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. Store In the Dark.
  • Storage buffer

    pH: 7.3
    Preservative: 0.02% Sodium azide
    Constituents: Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab240489 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 40 kDa.

Target

  • Function

    Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature.
  • Tissue specificity

    Brain, mostly in frontal cortex. Expressed at high level in fetal cerebellum.
  • Sequence similarities

    Belongs to the endophilin family.
    Contains 1 BAR domain.
    Contains 1 SH3 domain.
  • Domain

    An N-terminal amphipathic helix, the BAR domain and a second amphipathic helix inserted into helix 1 of the BAR domain (N-BAR domain) induce membrane curvature and bind curved membranes. The BAR domain dimer forms a rigid crescent shaped bundle of helices with the pair of second amphipathic helices protruding towards the membrane-binding surface.
  • Cellular localization

    Cytoplasm. Membrane. Concentrated in presynaptic nerve terminals in neurons.
  • Information by UniProt
  • Database links

  • Alternative names

    • bA335L15.1 (SH3 domain GRB2 like 2) antibody
    • CNSA2 antibody
    • EEN B1 antibody
    • EEN-B1 antibody
    • Endophilin 1 antibody
    • Endophilin A1 antibody
    • Endophilin A1 BAR domain antibody
    • Endophilin-1 antibody
    • Endophilin-A1 antibody
    • FLJ20276 antibody
    • FLJ25015 antibody
    • OTTHUMP00000021084 antibody
    • SH3 domain containing GRB2 like protein 2 antibody
    • SH3 domain GRB2 like 2 antibody
    • SH3 domain protein 2A antibody
    • SH3 domain-containing GRB2-like protein 2 antibody
    • SH3D2A antibody
    • SH3G2_HUMAN antibody
    • Sh3gl2 antibody
    • Sh3p4 antibody
    • SH3PA antibody
    see all

Images

  • Anti-SH3GL2 antibody (Biotin) (ab240489) at 0.3 µg/ml + Human frontal cortex lysate in RIPA buffer at 35 µg

    Predicted band size: 40 kDa



    Primary incubation was 1 hour. Detected by chemiluminescence.

References

ab240489 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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