Overview

  • Product name

  • Description

    Rabbit polyclonal to SHMT2/SHMT
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human SHMT2/SHMT aa 1-483.
    Database link: P34897

  • Positive control

    • 293T and HeLa whole cell lysates, HeLa cells, HeLa xenograft
  • General notes

     This product was previously labelled as SHMT2

     

Properties

Applications

Our Abpromise guarantee covers the use of ab155230 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/100 - 1/1000.
WB 1/5000 - 1/20000. Predicted molecular weight: 56 kDa.
IHC-P 1/100 - 1/1000.

Target

  • Function

    Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Interconversion of serine and glycine. Associates with mitochondrial DNA.
  • Pathway

    One-carbon metabolism; tetrahydrofolate interconversion.
  • Sequence similarities

    Belongs to the SHMT family.
  • Cellular localization

    Mitochondrion. Mitochondrion matrix > mitochondrion nucleoid. Mitochondrion inner membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Epididymis secretory sperm binding protein Li 51e antibody
    • GLY A+ antibody
    • GLYA antibody
    • glycine auxotroph A, human complement for hamster antibody
    • Glycine hydroxymethyltransferase antibody
    • GLYM_HUMAN antibody
    • HEL S 51e antibody
    • mitochondrial antibody
    • Serine hydroxymethyltransferase 2 (mitochondrial) antibody
    • Serine hydroxymethyltransferase antibody
    • Serine hydroxymethyltransferase mitochondrial antibody
    • Serine methylase antibody
    • SHMT 2 antibody
    • SHMT antibody
    • SHMT2 antibody
    see all

Images

  • All lanes : Anti-SHMT2/SHMT antibody (ab155230) at 1/10000 dilution

    Lane 1 : 293T whole cell lysate
    Lane 2 : HeLa whole cell lysate

    Lysates/proteins at 10 µg per lane.

    Predicted band size: 56 kDa



    7.5% SDS PAGE
  • Immunofluorescent analysis of methanol-fixed HeLa cells labeling SHMT2/SHMT with ab155230 at 1/500. Image at the bottom costained with Hoechst 33342.

  • Immunohistochemical analysis of paraffin embedded HeLa xenograft labeling SHMT2/SHMT with ab155230 antibody at 1/500.

References

ab155230 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab155230.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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