Overview

  • Product name

  • Description

    Rabbit polyclonal to SHQ1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    A 17 amino acid synthetic peptide near the amino terminus of Human SHQ1 (NP_060600).

  • Positive control

    • Human heart tissue lysate.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab139806 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 65 kDa.

Target

  • Function

    Required for the quantitative accumulation of H/ACA ribonucleoproteins (RNPs), including telomerase, probably through the stabilization of DKC1, from the time of its synthesis until its association with NOP10, NHP2, and NAF1 at the nascent H/ACA RNA.
  • Sequence similarities

    Belongs to the SHQ1 family.
    Contains 1 CS domain.
  • Cellular localization

    Cytoplasm > cytosol. Nucleus > nucleoplasm. May at least partially shuttle between cytosol and nucleoplasm. In the nucleoplasm, exhibits a granular pattern, but is excluded from nucleoli and Cajal bodies. Absent from most H/ACA-box RNA transcription sites.
  • Information by UniProt
  • Database links

  • Alternative names

    • FLJ10539 antibody
    • Protein SHQ1 homolog antibody
    • shq1 antibody
    • SHQ1 homolog (S. cerevisiae) antibody
    • SHQ1 homolog antibody
    • SHQ1, H/ACA ribonucleoprotein assembly factor antibody
    • SHQ1_HUMAN antibody
    • Shq1p antibody
    see all

Images

  • Immunofluorescence of SHQ1 in Human heart tissue with ab139806 at 20 ug/mL.
  • All lanes : Anti-SHQ1 antibody (ab139806) at 1 µg/ml

    Lane 1 : Human heart tissue lysate
    Lane 2 : Human heart tissue lysate with blocking peptide

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 65 kDa

References

ab139806 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab139806.
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