Key features and details
- Mouse monoclonal  to Sialoadhesin/CD169
- Suitable for: Flow Cyt, IP, WB, Functional Studies, IHC-Fr
- Reacts with: Human
- Isotype: IgG1
Product nameAnti-Sialoadhesin/CD169 antibody 
See all Sialoadhesin/CD169 primary antibodies
DescriptionMouse monoclonal  to Sialoadhesin/CD169
Tested applicationsSuitable for: Flow Cyt, IP, WB, Functional Studies, IHC-Frmore details
Species reactivityReacts with: Human
Tissue, cells or virus corresponding to Human Sialoadhesin/CD169. Human rhinovirus 14-infected monocyte-derived dendritic cells
Database link: Q9BZZ2
This product was previously labelled as Sialoadhesin
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.0975% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityProtein A purified
Purification notesPurity: > 95% (by SDS-PAGE)
Our Abpromise guarantee covers the use of ab199401 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use at an assay dependent concentration.
ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
|IP||Use at an assay dependent concentration.|
|WB||Use at an assay dependent concentration. Predicted molecular weight: 183 kDa.|
|Functional Studies||Use at an assay dependent concentration.
Inhibition of erythrocyte rosetting with cells expressing Sialoadhesin
|IHC-Fr||Use at an assay dependent concentration.|
FunctionActs as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid (By similarity). Binds to SPN/CD43 on T-cells (By similarity). May play a role in hemopoiesis.
Tissue specificityExpressed by macrophages in various tissues. High levels are found in spleen, lymph node, perivascular macrophages in brain and lower levels in bone marrow, liver Kupffer cells and lamina propria of colon and lung. Also expressed by inflammatory macrophages in rheumatoid arthritis.
Sequence similaritiesBelongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
Contains 16 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Cellular localizationSecreted and Cell membrane.
- Information by UniProt
- CD169 antibody
- CD169 antigen antibody
- dJ1009E24.1 antibody
ab199401 has not yet been referenced specifically in any publications.