Key features and details
- Potent, competitive methyltransferase inhibitor
- CAS Number: 58944-73-3
- Purity: > 98%
- Soluble in water
- Form / State: Solid
- Source: Synthetic
Product nameSinefungin, methyltransferase inhibitor
DescriptionPotent, competitive methyltransferase inhibitor
Potent, competitive methyltransferase inhibitor (IC50 values are < 1 and 2.5 μM for PRMT1 abd SET7/9 respectively). Nucleoside S-adenosylmethionine analog. Inhibits RNA synthesis. Shows antibacterial effects.
Chemical name(2S,5S)-2,5-Diamino-6-[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]hexanoic acid
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Epigenetics and Nuclear Signaling
- Nuclear Signaling Pathways
- Nuclear Receptors
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab144518 has been referenced in 1 publication.
- Azizi H et al. The Pumilio-domain protein PUF6 contributes to SIDER2 retroposon-mediated mRNA decay in Leishmania. RNA 23:1874-1885 (2017). PubMed: 28877997