Overview

  • Product name

    Sinomenine (Cuccoline), mu-opioid receptor activator
  • Description

    Morphinan analog. μ-opioid receptor activator.
  • Biological description

    Morphinan analog. μ-opioid receptor activator. Induces mast cell degranulation. Releases histamine and suppresses proinflammatory cytokine production. Shows anti-inflammatory, antinociceoptive and antineuropathic analgesic effects in vivo.
  • Purity

    > 99%
  • CAS Number

    115-53-7
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (9α,13α,14α)-7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one
  • Molecular weight

    329.39
  • Molecular formula

    C19H23NO4
  • PubChem identifier

    5459308
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CN1CCC23CC(=O)C(=CC2C1CC4=C3C(=C(C=C4)OC)O)OC
  • Source

    Synthetic

  • Research areas

References

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