Key features and details
- Sirtuin and NAD+-dependent class III HDAC inhibitor
- CAS Number: 143034-06-4
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameSIRT inhibitor 1/2 VII
DescriptionSirtuin and NAD+-dependent class III HDAC inhibitor
Sirtuin and NAD+-dependent class III HDAC inhibitor (IC50 values are 13.2 and 9.1 µM for SIRT1 and SIRT2, respectively). Thiobarbiturate compound.
Storage instructionsStore at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Epigenetics and Nuclear Signaling
- Chromatin Modifying Enzymes
- Class III / Sir2 class
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab144550 has not yet been referenced specifically in any publications.