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ab12193 has been referenced in 43 publications.

  • Di Emidio G  et al. SIRT1 participates in the response to methylglyoxal-dependent glycative stress in mouse oocytes and ovary. Biochim Biophys Acta Mol Basis Dis N/A:N/A (2019). WB ; Mouse . PubMed: 30771486
  • Liu GZ  et al. Aldosterone stimulation mediates cardiac metabolism remodeling via Sirt1/AMPK signaling in canine model. Naunyn Schmiedebergs Arch Pharmacol N/A:N/A (2019). PubMed: 30852656
  • Yang Y  et al. White light emitting diode induces autophagy in hippocampal neuron cells through GSK-3-mediated GR and RORa pathways. Aging (Albany NY) 11:1832-1849 (2019). PubMed: 30923260
  • Liu HW  et al. Exercise training upregulates SIRT1 to attenuate inflammation and metabolic dysfunction in kidney and liver of diabetic db/db mice. Nutr Metab (Lond) 16:22 (2019). PubMed: 30988688
  • Wang X  et al. Astragaloside IV inhibits glucose-induced epithelial-mesenchymal transition of podocytes through autophagy enhancement via the SIRT-NF-?B p65 axis. Sci Rep 9:323 (2019). PubMed: 30674969
  • Qian M  et al. Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria. Elife 7:N/A (2018). PubMed: 29717979
  • Liu Y  et al. Protective Effect of Hydrogen on Sodium Iodate-Induced Age-Related Macular Degeneration in Mice. Front Aging Neurosci 10:389 (2018). PubMed: 30564112
  • Saidi D  et al. Glioma-induced SIRT1-dependent activation of hMOF histone H4 lysine 16 acetyltransferase in microglia promotes a tumor supporting phenotype. Oncoimmunology 7:e1382790 (2018). PubMed: 29308302
  • Zhang Z  et al. Resolvin D1 promotes corneal epithelial wound healing and restoration of mechanical sensation in diabetic mice. Mol Vis 24:274-285 (2018). PubMed: 29643724
  • Fourcade S  et al. Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance. Aging Cell 16:1404-1413 (2017). WB ; Mouse . PubMed: 28984064
  • Ramya S  et al. Maternal Diabetes Alters Expression of MicroRNAs that Regulate Genes Critical for Neural Tube Development. Front Mol Neurosci 10:237 (2017). PubMed: 28798665
  • Di Emidio G  et al. The Natural Carotenoid Crocetin and the Synthetic Tellurium Compound AS101 Protect the Ovary against Cyclophosphamide by Modulating SIRT1 and Mitochondrial Markers. Oxid Med Cell Longev 2017:8928604 (2017). PubMed: 29270246
  • Falone S  et al. Power frequency magnetic field promotes a more malignant phenotype in neuroblastoma cells via redox-related mechanisms. Sci Rep 7:11470 (2017). PubMed: 28904402
  • Zhou J  et al. microRNA-34a overexpression inhibits cell migration and invasion via regulating SIRT1 in hepatocellular carcinoma. Oncol Lett 14:6950-6954 (2017). PubMed: 29344126
  • Meliso FM  et al. SIRT1 regulates Mxd1 during malignant melanoma progression. Oncotarget 8:114540-114553 (2017). PubMed: 29383100
  • Monteagudo S  et al. DOT1L safeguards cartilage homeostasis and protects against osteoarthritis. Nat Commun 8:15889 (2017). PubMed: 28627522
  • Ryu D  et al. NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation. Sci Transl Med 8:361ra139 (2016). PubMed: 27798264
  • Ao R  et al. Altered microRNA-9 Expression Level is Directly Correlated with Pathogenesis of Nonalcoholic Fatty Liver Disease by Targeting Onecut2 and SIRT1. Med Sci Monit 22:3804-3819 (2016). WB ; Human . PubMed: 27756894
  • Kang K  et al. Carnosic acid slows photoreceptor degeneration in the Pde6b(rd10) mouse model of retinitis pigmentosa. Sci Rep 6:22632 (2016). IHC, WB . PubMed: 26961159
  • Zheng YC  et al. 1,2,3-Triazole-Dithiocarbamate Hybrids, a Group of Novel Cell Active SIRT1 Inhibitors. Cell Physiol Biochem 38:185-93 (2016). WB ; Human . PubMed: 26784898
  • Hato T  et al. The macrophage mediates the renoprotective effects of endotoxin preconditioning. J Am Soc Nephrol 26:1347-62 (2015). PubMed: 25398784
  • Gao J  et al. MicroRNA-204-5p-Mediated Regulation of SIRT1 Contributes to the Delay of Epithelial Cell Cycle Traversal in Diabetic Corneas. Invest Ophthalmol Vis Sci 56:1493-504 (2015). PubMed: 25613939
  • Ye T  et al. Green tea polyphenol (-)-epigallocatechin-3-gallate restores Nrf2 activity and ameliorates crescentic glomerulonephritis. PLoS One 10:e0119543 (2015). WB . PubMed: 25785827
  • Chen CW  et al. DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia. Nat Med 21:335-43 (2015). PubMed: 25822366
  • De Bonis ML  et al. SIRT1 is necessary for proficient telomere elongation and genomic stability of induced pluripotent stem cells. Stem Cell Reports 2:690-706 (2014). IP . PubMed: 24936455
  • Carnemolla A  et al. Contesting the dogma of an age-related heat shock response impairment: implications for cardiac-specific age-related disorders. Hum Mol Genet 23:3641-56 (2014). WB ; Mouse . PubMed: 24556212
  • Di Emidio G  et al. SIRT1 signalling protects mouse oocytes against oxidative stress and is deregulated during aging. Hum Reprod N/A:N/A (2014). PubMed: 24963165
  • Lo Sasso G  et al. Loss of Sirt1 function improves intestinal anti-bacterial defense and protects from colitis-induced colorectal cancer. PLoS One 9:e102495 (2014). WB ; Mouse . PubMed: 25013930
  • Stettner M  et al. Promoting myelination in an in vitro mouse model of the peripheral nerve system: the effect of wine ingredients. PLoS One 8:e66079 (2013). ICC/IF ; Rat . PubMed: 23762469
  • Wang Y  et al. Overexpression of SIRT1 promotes high glucose-attenuated corneal epithelial wound healing via p53 regulation of the IGFBP3/IGF-1R/AKT pathway. Invest Ophthalmol Vis Sci 54:3806-14 (2013). PubMed: 23661372
  • Bolasco G  et al. Cardioprotective mIGF-1/SIRT1 signaling induces hypertension, leukocytosis and fear response in mice. Aging (Albany NY) 4:402-16 (2012). PubMed: 22691943
  • Herranz D  et al. SIRT1 promotes thyroid carcinogenesis driven by PTEN deficiency. Oncogene : (2012). WB . PubMed: 22986535
  • Campagna M  et al. SIRT1 stabilizes PML promoting its sumoylation. Cell Death Differ 18:72-9 (2011). WB, ICC/IF ; Mouse . PubMed: 20577263
  • Kalakeche R  et al. Endotoxin uptake by s1 proximal tubular segment causes oxidative stress in the downstream s2 segment. J Am Soc Nephrol 22:1505-16 (2011). IHC-P ; Mouse . PubMed: 21784899
  • Berkovits BD & Wolgemuth DJ The first bromodomain of the testis-specific double bromodomain protein Brdt is required for chromocenter organization that is modulated by genetic background. Dev Biol 360:358-68 (2011). ICC/IF ; Mouse . PubMed: 22020252
  • Muñoz-Fontela C  et al. Acetylation is indispensable for p53 antiviral activity. Cell Cycle 10:3701-5 (2011). PubMed: 22033337
  • González-Rodríguez A  et al. Inhibition of PTP1B restores IRS1-mediated hepatic insulin signaling in IRS2-deficient mice. Diabetes 59:588-99 (2010). PubMed: 20028942
  • Palacios JA  et al. SIRT1 contributes to telomere maintenance and augments global homologous recombination. J Cell Biol 191:1299-313 (2010). WB, ChIP ; Mouse . PubMed: 21187328
  • Koike K  et al. Complete lack of vitamin C intake generates pulmonary emphysema in senescence marker protein-30 knockout mice. Am J Physiol Lung Cell Mol Physiol 298:L784-92 (2010). WB ; Mouse . PubMed: 20172953
  • Kashiwagi K  et al. DNA methyltransferase 3b preferentially associates with condensed chromatin. Nucleic Acids Res : (2010). WB ; Human . PubMed: 20923784
  • Herranz D  et al. Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer. Nat Commun 1:3 (2010). PubMed: 20975665
  • Pfluger PT  et al. Sirt1 protects against high-fat diet-induced metabolic damage. Proc Natl Acad Sci U S A 105:9793-8 (2008). WB ; Mouse . PubMed: 18599449

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