Overview

  • Product name

  • Description

    Rabbit polyclonal to SIVA
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human SIVA aa 1-110.
    Database link: O15304

  • Positive control

    • IHC: Human small intestine and testis tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.3
    Preservative: 0.02% Sodium azide
    Constituents: 50% Glycerol, PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab224595 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/200.

Target

  • Function

    Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.
  • Tissue specificity

    Ubiquitous. Mostly expressed in thymus, testis, ovary, prostate, small intestine and spleen and less in colon.
  • Post-translational
    modifications

    Phosphorylated by ABL2/ARG in response to oxidative stress.
  • Cellular localization

    Cytoplasm. Nucleus. In the nucleus, accumulates in dot-like structures.
  • Information by UniProt
  • Database links

  • Alternative names

    • Apoptosis regulatory protein Siva antibody
    • CD27 binding (Siva) protein antibody
    • CD27-binding protein antibody
    • CD27BP antibody
    • Siva 1 antibody
    • Siva 2 antibody
    • SIVA_HUMAN antibody
    • Siva1 antibody
    see all

Images

  • Paraffin-embedded human small intestine tissue stained for SIVA using ab224595 at 1/100 dilution in immunohistochemical analysis.

  • Paraffin-embedded human testis tissue stained for SIVA using ab224595 at 1/100 dilution in immunohistochemical analysis.

References

ab224595 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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