Key features and details
- Rabbit polyclonal to SKIP
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-SKIP antibody
See all SKIP primary antibodies
DescriptionRabbit polyclonal to SKIP
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Recombinant fragment, corresponding to amino acids 183-430 of Human SKIP (BC004362).
- Human fetal heart lysate; Human fetal skeletal muscle tissue.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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FormLyophilized:Reconstitute in 200ul sterile H2O
Storage instructionsShipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituent: 1% BSA
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab113441 is purified by a protein affinity column.
Our Abpromise guarantee covers the use of ab113441 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Detects a band of approximately 51 kDa (predicted molecular weight: 51 kDa).|
|IHC-P||1/100 - 1/500.|
FunctionInositol 5-phosphatase which acts on inositol 1,4,5-trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-triphosphate. Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5-trisphosphate. May negatively regulate assembly of the actin cytoskeleton.
Tissue specificityUbiquitously expressed with highest levels in skeletal muscle, heart and kidney.
Sequence similaritiesBelongs to the inositol-1,4,5-trisphosphate 5-phosphatase type II family.
Cellular localizationEndoplasmic reticulum. Following stimulation with EGF, translocates to membrane ruffles.
- Information by UniProt
- 43 kDa form skeletal muscle and kidney enriched inositol phosphatase antibody
- Inositol polyphosphate 5-phosphatase K antibody
- INP5K_HUMAN antibody
ab113441 has not yet been referenced specifically in any publications.