Key features and details
- Mouse polyclonal to SLAMF7/CS1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-SLAMF7/CS1 antibody
See all SLAMF7/CS1 primary antibodies
DescriptionMouse polyclonal to SLAMF7/CS1
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Full length protein corresponding to Human SLAMF7/CS1 aa 1-297.
- SLAMF7/CS1 transfected 293T cell lysate.
This product was previously labelled as SLAMF7
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.4
Constituent: 2.68% PBS
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab67135 in the following tested applications.
|WB||1/500 - 1/1000. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa).|
RelevanceSLAMF7 contains one Ig-like C2-type (immunoglobulin-like) domain. Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway. It may play a role in lymphocyte adhesion. Isoform 3 does not mediate any activation. SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro). SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines. The isoform 3 is expressed at much lower level than isoform 1. There are three named isoforms.
Cellular localizationMembrane; Single-pass type I membrane protein.
- 19A antibody
- 19A24 protein antibody
- CD 319 antibody
All lanes : Anti-SLAMF7/CS1 antibody (ab67135) at 1/500 dilution
Lane 1 : SLAMF7/CS1 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 25 µg/ml per lane.
All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Predicted band size: 37 kDa
Observed band size: 37 kDa
ab67135 has been referenced in 1 publication.
- Xia Z et al. Integrated DNA methylation and gene expression analysis identifies SLAMF7 as a key regulator of atherosclerosis. Aging (Albany NY) 10:1324-1337 (2018). PubMed: 29905534