Anti-SLC10A2 antibody - N-terminal (ab174610)

Overview

  • Product name
    Anti-SLC10A2 antibody - N-terminal
    See all SLC10A2 primary antibodies
  • Description
    Rabbit polyclonal to SLC10A2 - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Synthetic peptide within Mouse SLC10A2 aa 38-65 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: P70172

  • Positive control
    • Mouse spleen tissue lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab174610 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 38 kDa.

Target

  • Function
    Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism.
  • Involvement in disease
    Defects in SLC10A2 are a cause of primary bile acid malabsorption (PBAM) [MIM:613291]. PBAM is an idiopathic intestinal disorder associated with congenital diarrhea, steatorrhea, interruption of the enterohepatic circulation of bile acids, and reduced plasma cholesterol levels.
  • Sequence similarities
    Belongs to the sodium:bile acid symporter family.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Apical sodium dependent bile acid transporter antibody
    • Apical sodium- dependent bile acid transporter antibody
    • Apical sodium-dependent bile acid transporter antibody
    • ASBT antibody
    • IBAT antibody
    • ileal antibody
    • ileal apical sodium-dependent bile acid transporter antibody
    • Ileal Na(+)/bile acid cotransporter antibody
    • Ileal sodium dependent bile acid transporter antibody
    • Ileal sodium-dependent bile acid transporter antibody
    • Ileal sodium/bile acid cotransporter antibody
    • ISBT antibody
    • Na(+)-dependent ileal bile acid transporter antibody
    • Na+ bile acid cotransporter antibody
    • Na+ dependent ileal bile acid transporter antibody
    • NTCP2 antibody
    • NTCP2_HUMAN antibody
    • PBAM antibody
    • SLC10A2 antibody
    • Sodium/taurocholate cotransporting polypeptide antibody
    • Sodium/taurocholate cotransporting polypeptide, ileal antibody
    • solute carrier family 10 (sodium/bile acid cotransporter family) antibody
    • Solute carrier family 10 (sodium/bile acid cotransporter family), member 2 antibody
    • Solute carrier family 10 member 2 antibody
    see all

Images

  • Anti-SLC10A2 antibody - N-terminal (ab174610) at 1/100 dilution + Mouse spleen tissue lysate at 35 µg

    Predicted band size: 38 kDa

References

ab174610 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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