Overview

  • Product name

    Anti-SLC10A2/ASBT antibody
    See all SLC10A2/ASBT primary antibodies
  • Description

    Goat polyclonal to SLC10A2/ASBT
  • Host species

    Goat
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Gorilla, Common marmoset, Orangutan
  • Immunogen

    Synthetic peptide corresponding to Human SLC10A2/ASBT aa 337-348 (C terminal) (Cysteine residue).
    Sequence:

    YKANGGFQPDEK


    Database link: NP_000443.1

  • Positive control

    • Human Small Intestine tissue
  • General notes

     This product was previously labelled as SLC10A2

     

Properties

Applications

Our Abpromise guarantee covers the use of ab134837 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism.
  • Involvement in disease

    Defects in SLC10A2 are a cause of primary bile acid malabsorption (PBAM) [MIM:613291]. PBAM is an idiopathic intestinal disorder associated with congenital diarrhea, steatorrhea, interruption of the enterohepatic circulation of bile acids, and reduced plasma cholesterol levels.
  • Sequence similarities

    Belongs to the sodium:bile acid symporter family.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Apical sodium dependent bile acid transporter antibody
    • Apical sodium- dependent bile acid transporter antibody
    • Apical sodium-dependent bile acid transporter antibody
    • ASBT antibody
    • IBAT antibody
    • ileal antibody
    • ileal apical sodium-dependent bile acid transporter antibody
    • Ileal Na(+)/bile acid cotransporter antibody
    • Ileal sodium dependent bile acid transporter antibody
    • Ileal sodium-dependent bile acid transporter antibody
    • Ileal sodium/bile acid cotransporter antibody
    • ISBT antibody
    • Na(+)-dependent ileal bile acid transporter antibody
    • Na+ bile acid cotransporter antibody
    • Na+ dependent ileal bile acid transporter antibody
    • NTCP2 antibody
    • NTCP2_HUMAN antibody
    • PBAM antibody
    • SLC10A2 antibody
    • Sodium/taurocholate cotransporting polypeptide antibody
    • Sodium/taurocholate cotransporting polypeptide, ileal antibody
    • solute carrier family 10 (sodium/bile acid cotransporter family) antibody
    • Solute carrier family 10 (sodium/bile acid cotransporter family), member 2 antibody
    • Solute carrier family 10 member 2 antibody
    see all

Images

  • Immunohistochemistry analysis of formalin fixed, paraffin embedded Human small intestine tissue labelling SLC10A2/ASBT with ab134837 at 3.75 µg/ml.

References

ab134837 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab134837.
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