Anti-SLC12A6/KCC3 antibody (ab225990)
- Datasheet
- References
- Protocols
Overview
-
Product name
Anti-SLC12A6/KCC3 antibody
See all SLC12A6/KCC3 primary antibodies -
Description
Rabbit polyclonal to SLC12A6/KCC3 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment corresponding to Human SLC12A6/KCC3 aa 60-190.
Database link: Q9UHW9 -
Positive control
- IHC-P: Human kidney tissue.
-
General notes
This product was previously labelled as SLC12A6
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.3
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab225990 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | 1/20 - 1/200. |
Target
-
Function
Mediates electroneutral potassium-chloride cotransport. May be activated by cell swelling. May contribute to cell volume homeostasis in single cells. -
Tissue specificity
Highly expressed in heart, brain and kidney. Detected at lower levels in skeletal muscle, placenta, lung and pancreas. Detected in umbilical vein endothelial cells. Isoform 2 is more abundant in kidney. Isoform 5 is testis specific. Expressed in the proximal tubule of the kidney (at protein level). -
Involvement in disease
Agenesis of the corpus callosum, with peripheral neuropathy -
Sequence similarities
Belongs to the SLC12A transporter family. -
Post-translational
modificationsN-glycosylated. -
Cellular localization
Basolateral cell membrane. - Information by UniProt
-
Database links
- Entrez Gene: 9990 Human
- Omim: 604878 Human
- SwissProt: Q9UHW9 Human
- Unigene: 510939 Human
-
Alternative names
- ACCPN antibody
- Electroneutral potassium-chloride cotransporter 3 antibody
- Furosemide sensitive KCl cotransporter 3 antibody
see all
Images
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SLC12A6/KCC3 antibody (ab225990)Paraffin embedded human kidney tissue stained for SLC12A6/KCC3 with ab225990 (1/100 dilution) in immunohistochemical analysis.
Datasheets and documents
References
ab225990 has not yet been referenced specifically in any publications.
