Key features and details
- Rabbit polyclonal to SLC12A6/KCC3 - C-terminal
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-SLC12A6/KCC3 antibody - C-terminal
See all SLC12A6/KCC3 primary antibodies
DescriptionRabbit polyclonal to SLC12A6/KCC3 - C-terminal
SpecificityNo cross reactivity with other proteins.
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
- HeLa and HUT102 cell lysate.
This product was previously labelled as SLC12A6
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azide
Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab191451 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 128 kDa.|
FunctionMediates electroneutral potassium-chloride cotransport. May be activated by cell swelling. May contribute to cell volume homeostasis in single cells.
Tissue specificityHighly expressed in heart, brain and kidney. Detected at lower levels in skeletal muscle, placenta, lung and pancreas. Detected in umbilical vein endothelial cells. Isoform 2 is more abundant in kidney. Isoform 5 is testis specific. Expressed in the proximal tubule of the kidney (at protein level).
Involvement in diseaseAgenesis of the corpus callosum, with peripheral neuropathy
Sequence similaritiesBelongs to the SLC12A transporter family.
Cellular localizationBasolateral cell membrane.
- Information by UniProt
- ACCPN antibody
- Electroneutral potassium-chloride cotransporter 3 antibody
- Furosemide sensitive KCl cotransporter 3 antibody
ab191451 has not yet been referenced specifically in any publications.