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Signal Transduction Metabolism Plasma Membrane Channels
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Anti-SLC14A1/UTE antibody - N-terminal (ab198743)

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Western blot - Anti-SLC14A1/UTE antibody - N-terminal (ab198743)

    Key features and details

    • Rabbit polyclonal to SLC14A1/UTE - N-terminal
    • Suitable for: WB
    • Reacts with: Mouse, Human
    • Isotype: IgG

    You may also be interested in

    Protein
    Product image
    Recombinant Human SLC14A1/UTE protein (ab159533)
    Secondary
    Product image
    Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

    View more associated products

    Overview

    • Product name

      Anti-SLC14A1/UTE antibody - N-terminal
      See all SLC14A1/UTE primary antibodies
    • Description

      Rabbit polyclonal to SLC14A1/UTE - N-terminal
    • Host species

      Rabbit
    • Specificity

      ab198743 detects endogenous levels of total SLC14A1/UTE protein.

    • Tested applications

      Suitable for: WBmore details
    • Species reactivity

      Reacts with: Mouse, Human
    • Immunogen

      Synthetic peptide within Human SLC14A1/UTE (N terminal). The exact sequence is proprietary.
      Database link: Q13336

    • Positive control

      • Mouse kidney tissue lysate
    • General notes

       This product was previously labelled as SLC14A1

       

      Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

      Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

      We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

      In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

      We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

      Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

      Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

    Properties

    • Form

      Liquid
    • Storage instructions

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
    • Storage buffer

      pH: 7.4
      Preservative: 0.05% Sodium azide
      Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS
    • Concentration information loading...
    • Purity

      Immunogen affinity purified
    • Clonality

      Polyclonal
    • Isotype

      IgG
    • Research areas

      • Signal Transduction
      • Metabolism
      • Plasma Membrane
      • Channels
      • Cardiovascular
      • Blood
      • Blood Cell Antigens
      • RBC Antigens
      • Blood Group Antigens

    Associated products

    • Compatible Secondaries

      • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
      • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
    • Isotype control

      • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
    • Positive Controls

      • Mouse kidney normal tissue lysate - total protein (ab29305)
    • Recombinant Protein

      • Recombinant Human SLC14A1/UTE protein (ab159533)
    • Related Products

      • Recombinant Human SLC14A1/UTE protein (ab159533)

    Applications

    Our Abpromise guarantee covers the use of ab198743 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    WB 1/200 - 1/1000. Predicted molecular weight: 43 kDa.

    Target

    • Function

      Urea channel that facilitates transmembrane urea transport down a concentration gradient. A constriction of the transmembrane channel functions as selectivity filter through which urea is expected to pass in dehydrated form. The rate of urea conduction is increased by hypotonic stress. Plays an important role in the kidney medulla collecting ducts, where it allows rapid equilibration between the lumen of the collecting ducts and the interstitium, and thereby prevents water loss driven by the high concentration of urea in the urine. Facilitates urea transport across erythrocyte membranes. May also play a role in transmembrane water transport, possibly by indirect means.
    • Tissue specificity

      Detected in erythrocytes (at protein level). Erythrocytes.
    • Sequence similarities

      Belongs to the urea transporter family.
    • Cellular localization

      Cell membrane. Basolateral cell membrane. Restricted to the basolateral membrane in various portions of the urothelium.
    • Target information above from: UniProt accession Q13336 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 6563 Human
      • Entrez Gene: 108052 Mouse
      • Omim: 111000 Human
      • SwissProt: Q13336 Human
      • SwissProt: Q8VHL0 Mouse
      • Unigene: 101307 Human
      • Unigene: 33832 Mouse
      • Alternative names

        • blood group Kidd urea transporter antibody
        • erythrocyte antibody
        • HsT1341 antibody
        • HUT11 antibody
        • JK antibody
        • Kidd antibody
        • kidd (JK) blood group urea transporter B1 antibody
        • RACH1 antibody
        • Slc14a1 antibody
        • solute carrier family 14 (urea transporter) member 1 (Kidd blood group) antibody
        • Solute carrier family 14 member 1 antibody
        • Urea transporter 1 antibody
        • Urea transporter antibody
        • urea transporter B1 antibody
        • Urea transporter erythrocyte antibody
        • urea transporter JK glycoprotein antibody
        • UT B1 antibody
        • UT1 antibody
        • UT1_HUMAN antibody
        • UTE antibody
        see all

      Images

      • Western blot - Anti-SLC14A1/UTE antibody - N-terminal (ab198743)
        Western blot - Anti-SLC14A1/UTE antibody - N-terminal (ab198743)
        Anti-SLC14A1/UTE antibody - N-terminal (ab198743) at 1/200 dilution + Mouse kidney tissue lysate at 40 µg

        Predicted band size: 43 kDa


        Exposure time: 2 minutes

      Protocols

      • Western blot protocols

      Click here to view the general protocols

      Datasheets and documents

      • Datasheet
    • References (0)

      Publishing research using ab198743? Please let us know so that we can cite the reference in this datasheet.

      ab198743 has not yet been referenced specifically in any publications.

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