• Product name

    Anti-SLC1A5/ASCT2 antibody
    See all SLC1A5/ASCT2 primary antibodies
  • Description

    Rabbit polyclonal to SLC1A5/ASCT2
  • Host species

  • Tested applications

    Suitable for: IP, WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Chimpanzee, Orangutan
  • Immunogen

    Synthetic peptide within Human SLC1A5/ASCT2 aa 450-500. The exact sequence is proprietary. (NP_005619.1).


    Database link: Q15758

  • Positive control

    • HeLa, 293T and Jurkat whole cell lysate (ab7899).
  • General notes

     This product was previously labelled as SLC1A5




Our Abpromise guarantee covers the use of ab187692 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-10 µg/mg of lysate.
WB 1/2000 - 1/10000. Predicted molecular weight: 56 kDa.


  • Function

    Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. May also be activated by insulin. Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904). Acts as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses (PubMed:10051606, PubMed:10196349).
  • Tissue specificity

    Placenta, lung, skeletal muscle, kidney, pancreas, and intestine.
  • Sequence similarities

    Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. SLC1A5 subfamily.
  • Cellular localization

    Cell membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt
  • Database links

  • Alternative names

    • ASCT2 antibody
    • AAAT antibody
    • AAAT_HUMAN antibody
    • ATB(0) antibody
    • ATBO antibody
    • Baboon M7 virus receptor antibody
    • FLJ31068 antibody
    • M7V1 antibody
    • M7VS1 antibody
    • Neutral amino acid transporter B(0) antibody
    • R16 antibody
    • RD114/simian type D retrovirus receptor antibody
    • RDR antibody
    • RDRC antibody
    • SLC1A5 antibody
    • Sodium dependent neutral amino acid transporter type 2 antibody
    • Sodium-dependent neutral amino acid transporter type 2 antibody
    • Solute carrier family 1 (neutral amino acid transporter), member 5 antibody
    • Solute carrier family 1 member 5 antibody
    see all


  • All lanes : Anti-SLC1A5/ASCT2 antibody (ab187692) at 0.1 µg/ml

    Lane 1 : HeLa whole cell lysate
    Lane 2 : 293T whole cell lysate
    Lane 3 : Jurkat whole cell lysate

    Lysates/proteins at 50 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 56 kDa

    Exposure time: 3 minutes
  • Detection of SLC1A5/ASCT2 in Immunoprecipitates of 293T whole cell lysate (1 mg for IP, 20% of IP loaded) using ab187692 at 6 µg/mg lysate for IP and at 1 µg/ml for subsequent Western blot detection. Lane 2 represents control IgG IP. Detection: Chemiluminescence with an exposure time of 30 seconds.


This product has been referenced in:

  • Huang X  et al. The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance. Autophagy 15:1258-1279 (2019). Read more (PubMed: 30786811) »
  • Sen N  et al. EWS-FLI1 reprograms the metabolism of Ewing sarcoma cells via positive regulation of glutamine import and serine-glycine biosynthesis. Mol Carcinog 57:1342-1357 (2018). Read more (PubMed: 29873416) »
See all 2 Publications for this product

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