Overview

  • Product name
  • Description
    Rabbit polyclonal to SLC20A2
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cat
  • Immunogen

    Recombinant protein fragment, corresponding to an internal region within amino acids 133-420 of Human SLC20A2 (Uniprot ID Q08357)

  • Positive control
    • 293T, A431, H1299 and Raji cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab155259 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 70 kDa.

Target

  • Function
    Sodium-phosphate symporter which seems to play a fundamental housekeeping role in phosphate transport by absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. In vitro, sodium-dependent phosphate uptake is not siginificantly affected by acidic and alkaline conditions, however sodium-independent phosphate uptake occurs at acidic conditions. May play a role in extracellular matrix, cartilage and vascular calcification. Functions as a retroviral receptor and confers human cells susceptibility to infection to amphotropic murine leukemia virus (A-MuLV), 10A1 murine leukemia virus (10A1 MLV) and some feline leukemia virus subgroup B (FeLV-B) variants.
  • Tissue specificity
    Ubiquitously expressed.
  • Sequence similarities
    Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Gibbon ape leukemia virus receptor 2 antibody
    • Gibbon leukemia virus receptor 2 antibody
    • GLVR 2 antibody
    • GLVR-2 antibody
    • GLVR2 antibody
    • hPit2 antibody
    • IBGC3 antibody
    • MLVAR antibody
    • Murine leukemia virus amphotropic receptor antibody
    • murine leukemia virus, amphotropic, receptor for antibody
    • Phosphate transporter 2 antibody
    • PIT 2 antibody
    • PiT-2 antibody
    • Pit2 antibody
    • RAM1 antibody
    • S20A2_HUMAN antibody
    • SLC20A2 antibody
    • Sodium-dependent phosphate transporter 2 antibody
    • Solute carrier family 20 (phosphate transporter) member 2 antibody
    • solute carrier family 20 (phosphate transporter), member 2 antibody
    • Solute carrier family 20 member 2 antibody
    see all

Images

  • Anti-SLC20A2 antibody (ab155259) at 1/500 dilution + 293T whole cell lysate at 30 µg

    Predicted band size: 70 kDa



    7.5% SDS PAGE

References

This product has been referenced in:
  • Castella B  et al. The ATP-binding cassette transporter A1 regulates phosphoantigen release and V?9Vd2 T cell activation by dendritic cells. Nat Commun 8:15663 (2017). Read more (PubMed: 28580927) »
See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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