Overview

  • Product name
    Anti-SLC22A2 antibody [EPR11248]
    See all SLC22A2 primary antibodies
  • Description
    Rabbit monoclonal [EPR11248] to SLC22A2
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
    Unsuitable for: Flow Cyt,ICC or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human SLC22A2 aa 100-200. The exact sequence is proprietary.
    Database link: O15244

  • Positive control
    • Human fetal kidney lysate, 293T, HepG2 and A431 lysates, Human kidney tissue and Human prostate tissue
  • General notes

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.01% Sodium azide
    Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
  • Purity
    Tissue culture supernatant
  • Clonality
    Monoclonal
  • Clone number
    EPR11248
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab170871 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 63 kDa.
IHC-P 1/100 - 1/250. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
  • Application notes
    Is unsuitable for Flow Cyt,ICC or IP.
  • Target

    • Relevance
      SLC22A2 (solute carrier family 22 (organic cation transporter), member 2) is an organic cation transporter. Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. SLC22A2 is found primarily in the kidney, where it may mediate the first step in cation reabsorption. It plays important roles in the renal tubular secretion of cationic drugs.
    • Cellular localization
      Plasma membrane
    • Database links
    • Alternative names
      • MGC32628 antibody
      • OCT 2 antibody
      • OCT2 antibody
      • Organic cation transporter 2 antibody
      • Organic cation transporter antibody
      • RP11-317M22.2 antibody
      • Solute carrier family 22 (organic cation transporter) member 2 antibody
      • Solute carrier family 22 member 2 antibody
      see all

    Images

    • ab170871 showing +ve staining in Human uterus tissue.

    • ab170871 showing +ve staining in Human normal stomach tissue.

    • Immunohistochemical analysis of paraffin-embedded Human prostate tissue labeling SLC22A2 using ab170871 at a 1/100 dilution. 

    • Immunohistochemical analysis of paraffin-embedded Human kidney tissue labeling SLC22A2 using ab170871 at a 1/100 dilution.

    • ab170871 showing -ve staining in Human normal liver tissue.
    • All lanes : Anti-SLC22A2 antibody [EPR11248] (ab170871) at 1/1000 dilution

      Lane 1 : Human fetal kidney lysate
      Lane 2 : 293T lysate
      Lane 3 : HepG2 lysate
      Lane 4 : A431 lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labeled goat anti-rabbit IgG at 1/2000 dilution

      Predicted band size: 63 kDa

    References

    This product has been referenced in:
    • Sekhar GN  et al. Organic cation transporter 1 (OCT1) is involved in pentamidine transport at the human and mouse blood-brain barrier (BBB). PLoS One 12:e0173474 (2017). Read more (PubMed: 28362799) »
    See 1 Publication for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab170871.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up