Product nameAnti-SLC25A11 antibody
See all SLC25A11 primary antibodies
DescriptionRabbit polyclonal to SLC25A11
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Human
Predicted to work with: Rat, Sheep, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Zebrafish
- 721_B cell lysate.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 2% Sucrose, PBS
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab80464 is purified by a peptide affinity chromatography method.
- Pathways and Processes
- Metabolic signaling pathways
- Energy transfer pathways
- Energy Metabolism
Our Abpromise guarantee covers the use of ab80464 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 34 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.|
FunctionCatalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism.
Sequence similaritiesBelongs to the mitochondrial carrier family.
Contains 3 Solcar repeats.
Cellular localizationMitochondrion inner membrane.
- Information by UniProt
- M2OM_HUMAN antibody
- Mitochondrial 2 oxoglutarate/malate carrier protein antibody
- Mitochondrial 2-oxoglutarate/malate carrier protein antibody
This product has been referenced in:
- Agudelo LZ et al. Skeletal muscle PGC-1a1 reroutes kynurenine metabolism to increase energy efficiency and fatigue-resistance. Nat Commun 10:2767 (2019). Read more (PubMed: 31235694) »
- Kamga CK et al. Dicarboxylate carrier-mediated glutathione transport is essential for reactive oxygen species homeostasis and normal respiration in rat brain mitochondria. Am J Physiol Cell Physiol 299:C497-505 (2010). WB ; Mouse . Read more (PubMed: 20538765) »