Key features and details
- Rabbit polyclonal to SLC25A12
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-SLC25A12 antibody
See all SLC25A12 primary antibodies
DescriptionRabbit polyclonal to SLC25A12
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Recombinant fragment corresponding to Human SLC25A12 aa 202-317.
Database link: O75746
- WB: HEK-293 whole cell lysate. Mouse and rat heart and kidney tissue lysates. IHC-P: Human pancreatic cancer and brain tissues.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Constituents: 50% Glycerol, PBS, 0.03% Proclin 300
Concentration information loading...
PurityProtein G purified
Purification notesPurity >95%.
Our Abpromise guarantee covers the use of ab234975 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/20 - 1/200.|
|WB||1/500 - 1/5000. Predicted molecular weight: 74 kDa.|
FunctionCalcium-dependent mitochondrial aspartate and glutamate carrier. May have a function in the urea cycle.
Tissue specificityHigh levels in heart and skeletal muscle, low in brain and very low in kidney.
Involvement in diseaseDefects in SLC25A12 are the cause of aspartate-glutamate carrier 1 deficiency (AGC1D) [MIM:612949]; also called global cerebral hypomyelination. This syndrome consists of a child severe psychomotor retardation, hypotonia and hypomyelination of the central nervous system.
Sequence similaritiesBelongs to the mitochondrial carrier family.
Contains 4 EF-hand domains.
Contains 3 Solcar repeats.
Cellular localizationMitochondrion inner membrane.
- Information by UniProt
- AGC1 antibody
- Araceli hiperlarga antibody
- ARALAR antibody
All lanes : Anti-SLC25A12 antibody (ab234975) at 1/500 dilution
Lane 1 : HEK-293 (Human epithelial cell line from embryonic kidney) whole cell lysate
Lane 2 : Rat heart tissue lysate
Lane 3 : Rat kidney tissue lysate
Lane 4 : Mouse kidney tissue lysate
Lane 5 : Mouse heart tissue lysate
All lanes : Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 74 kDa
Paraffin-embedded human brain tissue stained for SLC25A12 with ab234975 at 1/100 dilution in immunohistochemical analysis.
Paraffin-embedded human pancreatic cancer tissue stained for SLC25A12 with ab234975 at 1/100 dilution in immunohistochemical analysis.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab234975 has not yet been referenced specifically in any publications.