Overview

  • Product name

    Anti-SLC25A25/APC3 antibody
    See all SLC25A25/APC3 primary antibodies
  • Description

    Rabbit polyclonal to SLC25A25/APC3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Recombinant fragment corresponding to Human SLC25A25/APC3 aa 1-189.
    Database link: Q6KCM7

  • Positive control

    • WB: Mouse liver and brain tissue lysates. IHC-P: Human prostate cancer. ICC/IF: U-251 MG cells.
  • General notes

     This product was previously labelled as SLC25A25

     

Properties

Applications

Our Abpromise guarantee covers the use of ab237051 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/200.
WB 1/500 - 1/2000. Predicted molecular weight: 52 kDa.
ICC/IF 1/50 - 1/200.

Target

  • Function

    Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria.
  • Tissue specificity

    Present in various cell lines (at protein level). Widely expressed. Expressed in fetal and adult liver, skeletal muscle, testis, ovary, hippocampus and caudate nucleus. Isoform 1 is present in all tissues tested. Isoform 2 expression is restricted to kidney and lung.
  • Sequence similarities

    Belongs to the mitochondrial carrier (TC 2.A.29) family.
    Contains 3 EF-hand domains.
    Contains 3 Solcar repeats.
  • Cellular localization

    Mitochondrion inner membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Calcium-binding mitochondrial carrier protein SCaMC-2 antibody
    • KIAA1896 antibody
    • MCSC antibody
    • MGC105138 antibody
    • MGC119514 antibody
    • MGC119515 antibody
    • MGC119516 antibody
    • MGC119517 antibody
    • Mitochondrial ATP Mg/Pi carrier antibody
    • Mitochondrial ATP-Mg/Pi carrier protein 3 antibody
    • Mitochondrial Ca(2+)-dependent solute carrier protein 3 antibody
    • Mitochondrial Ca2+ dependent solute carrier antibody
    • Mitochondrial calcium-dependent solute carrier antibody
    • PCSCL antibody
    • RP11 395P17.4 antibody
    • SCAMC 2 antibody
    • SCAMC2 antibody
    • SCMC2_HUMAN antibody
    • Short calcium binding mitochondrial carrier 2 antibody
    • SLC25A25 antibody
    • Small calcium binding mitochondrial carrier 2 antibody
    • Small calcium-binding mitochondrial carrier protein 2 antibody
    • Solute carrier family 25 (mitochondrial carrier phosphate carrier) member 25 antibody
    • Solute carrier family 25 member 25 antibody
    • solute carrier family 25, member 25, isoform a antibody
    see all

Images

  • All lanes : Anti-SLC25A25/APC3 antibody (ab237051) at 1/500 dilution

    Lane 1 : Mouse liver tissue lysate
    Lane 2 : Mouse brain tissue lysate

    Secondary
    All lanes : Goat polyclonal to Rabbit IgG at 1/10000 dilution

    Predicted band size: 52 kDa

  • Paraffin-embedded human prostate cancer tissue stained for SLC25A25/APC3 using ab237051 at 1/100 dilution in immunohistochemical analysis.

  • U-251 MG (human brain glioma cell line) cells stained for SLC25A25/APC3 (green) using ab237051 at 1/100 dilution in ICC/IF, followed by Alexa Fluor 488® conjugated Goat Anti-Rabbit IgG (H+L).

References

ab237051 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab237051.
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