Overview

  • Product name

    Anti-SLC25A38 antibody [EPBHMR1]
    See all SLC25A38 primary antibodies
  • Description

    Rabbit monoclonal [EPBHMR1] to SLC25A38
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human SLC25A38 aa 50-150. The exact sequence is proprietary.

  • Positive control

    • TF-1 cell lysate
  • General notes

    This antibody was developed as part of a collaboration between Epitomics, Sanford Burnham Medical Research Institute and the lab of Huaxi Xu.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab133614 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 33 kDa (predicted molecular weight: 33 kDa).
  • Application notes
    Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • Function

      Mitochondrial carrier required during erythropoiesis. Probably involved in the biosynthesis of heme, possibly by facilitating 5-aminolevulinate (ALA) production. May act by importing glycine into mitochondria or by exchanging glycine for ALA across the mitochondrial inner membrane.
    • Tissue specificity

      Preferentially expressed in erythroid cells.
    • Involvement in disease

      Anemia, sideroblastic, pyridoxine-refractory, autosomal recessive
    • Sequence similarities

      Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
      Contains 3 Solcar repeats.
    • Cellular localization

      Mitochondrion inner membrane.
    • Information by UniProt
    • Database links

    • Alternative names

      • FLJ20551 antibody
      • FLJ22703 antibody
      • S2538_HUMAN antibody
      • slc25a38 antibody
      • Solute carrier family 25 member 38 antibody
      see all

    Images

    • Anti-SLC25A38 antibody [EPBHMR1] (ab133614) at 1/1000 dilution + TF-1 cell lysate at 10 µg

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 33 kDa
      Observed band size: 33 kDa

    References

    This product has been referenced in:

    • Zhang C  et al. Appoptosin interacts with mitochondrial outer-membrane fusion proteins and regulates mitochondrial morphology. J Cell Sci 129:994-1002 (2016). Read more (PubMed: 26813789) »
    • Zhao Y  et al. Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis. Neuron 87:963-75 (2015). Read more (PubMed: 26335643) »
    See all 2 Publications for this product

    Customer reviews and Q&As

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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