Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPBHMR1] to SLC25A38
- Suitable for: WB
- Reacts with: Human
Product nameAnti-SLC25A38 antibody [EPBHMR1]
See all SLC25A38 primary antibodies
DescriptionRabbit monoclonal [EPBHMR1] to SLC25A38
Tested applicationsSuitable for: WBmore details
Unsuitable for: Flow Cyt,ICC,IHC-P or IP
Species reactivityReacts with: Human
Synthetic peptide within Human SLC25A38 aa 50-150. The exact sequence is proprietary.
- TF-1 cell lysate
This antibody was developed as part of a collaboration between Epitomics, Sanford Burnham Medical Research Institute and the lab of Huaxi Xu.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage bufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
Concentration information loading...
PurityTissue culture supernatant
Our Abpromise guarantee covers the use of ab133614 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/10000. Detects a band of approximately 33 kDa (predicted molecular weight: 33 kDa).|
FunctionMitochondrial carrier required during erythropoiesis. Probably involved in the biosynthesis of heme, possibly by facilitating 5-aminolevulinate (ALA) production. May act by importing glycine into mitochondria or by exchanging glycine for ALA across the mitochondrial inner membrane.
Tissue specificityPreferentially expressed in erythroid cells.
Involvement in diseaseAnemia, sideroblastic, pyridoxine-refractory, autosomal recessive
Sequence similaritiesBelongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
Contains 3 Solcar repeats.
Cellular localizationMitochondrion inner membrane.
- Information by UniProt
- FLJ20551 antibody
- FLJ22703 antibody
- S2538_HUMAN antibody
ab133614 has been referenced in 3 publications.
- Zhang C et al. Appoptosin Mediates Lesions Induced by Oxidative Stress Through the JNK-FoxO1 Pathway. Front Aging Neurosci 11:243 (2019). PubMed: 31551758
- Zhang C et al. Appoptosin interacts with mitochondrial outer-membrane fusion proteins and regulates mitochondrial morphology. J Cell Sci 129:994-1002 (2016). PubMed: 26813789
- Zhao Y et al. Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis. Neuron 87:963-75 (2015). PubMed: 26335643