Anti-SLC25A6 antibody (ab153956)
Key features and details
- Rabbit polyclonal to SLC25A6
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-SLC25A6 antibody
See all SLC25A6 primary antibodies -
Description
Rabbit polyclonal to SLC25A6 -
Host species
Rabbit -
Tested applications
Suitable for: WB, ICC/IFmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Chicken, Cow, Pig, Zebrafish
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Immunogen
Recombinant fragment, corresponding to a region within amino acids 57-298 of Human SLC25A6 (Uniprot ID P12236).
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Positive control
- Recombinant Human SLC25A6 protein (ab152181) can be used as a positive control in WB. NCI-H929 whole cell lysate; HeLa cells.
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab153956 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500 - 1/3000. Predicted molecular weight: 33 kDa. | |
| ICC/IF | 1/100 - 1/1000. |
Target
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Function
Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis. -
Sequence similarities
Belongs to the mitochondrial carrier family.
Contains 3 Solcar repeats. -
Cellular localization
Mitochondrion inner membrane. The complex formed with ARL2BP, ARL2 and SLC25A6 is expressed in mitochondria. - Information by UniProt
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Database links
- Entrez Gene: 374072 Chicken
- Entrez Gene: 282480 Cow
- Entrez Gene: 293 Human
- Entrez Gene: 403155 Pig
- Entrez Gene: 566370 Zebrafish
- Omim: 300151 Human
- Omim: 403000 Human
- SwissProt: P32007 Cow
see all -
Alternative names
- AAC3 antibody
- Adenine nucleotide translocator 3 antibody
- ADP antibody
see all
Images
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Western blot - Anti-SLC25A6 antibody (ab153956)Anti-SLC25A6 antibody (ab153956) at 1/1000 dilution + NCI-H929 whole cell lysate at 10 µg
Predicted band size: 33 kDa
12% SDS PAGE -
Immunocytochemistry/ Immunofluorescence - Anti-SLC25A6 antibody (ab153956)Immunofluorescence analysis of methanol-fixed HeLa, labeling SLC25A6 with ab153956 at 1/500 dilution. Blue: Hoechst 33342 staining.
Protocols
References (1)
ab153956 has been referenced in 1 publication.
- Lin C et al. Caspase-Dependent Apoptosis Induction via Viral Protein ORF4 of Porcine Circovirus 2 Binding to Mitochondrial Adenine Nucleotide Translocase 3. J Virol 92:N/A (2018). PubMed: 29491154
