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    slc25a6-antibody-ab154007.pdf

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Cell Biology Apoptosis Intracellular Associated Proteins
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Anti-SLC25A6 antibody (ab154007)

  • Datasheet
  • SDS
Submit a review Submit a question References (3)

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Western blot - Anti-SLC25A6 antibody (ab154007)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SLC25A6 antibody (ab154007)
  • Immunocytochemistry/ Immunofluorescence - Anti-SLC25A6 antibody (ab154007)

Key features and details

  • Rabbit polyclonal to SLC25A6
  • Suitable for: WB, IHC-P, ICC/IF
  • Reacts with: Human
  • Isotype: IgG

You may also be interested in

Secondary
Product image
Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

View more associated products

Overview

  • Product name

    Anti-SLC25A6 antibody
    See all SLC25A6 primary antibodies
  • Description

    Rabbit polyclonal to SLC25A6
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Cow
  • Immunogen

    Recombinant fragment corresponding to a region within amino acids 1-298 of Human SLC25A6 (UniProt ID: P12236).

  • Positive control

    • 293T whole cell lysate, HeLa cells, Cal27 xenograft
  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.00
    Preservative: 0.025% Proclin 300
    Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine)
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Cell Biology
    • Apoptosis
    • Intracellular
    • Associated Proteins
    • Tags & Cell Markers
    • Subcellular Markers
    • Organelles
    • Mitochondria
    • Signal Transduction
    • Metabolism
    • Mitochondrial
    • Metabolism
    • Pathways and Processes
    • Mitochondrial Metabolism
    • Mitochondrial markers

Associated products

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab154007 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
1/500 - 1/3000. Predicted molecular weight: 33 kDa.
IHC-P
1/100 - 1/1000.
ICC/IF
1/100 - 1/1000.
Notes
WB
1/500 - 1/3000. Predicted molecular weight: 33 kDa.
IHC-P
1/100 - 1/1000.
ICC/IF
1/100 - 1/1000.

Target

  • Function

    Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
  • Sequence similarities

    Belongs to the mitochondrial carrier family.
    Contains 3 Solcar repeats.
  • Cellular localization

    Mitochondrion inner membrane. The complex formed with ARL2BP, ARL2 and SLC25A6 is expressed in mitochondria.
  • Target information above from: UniProt accession P12236 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 282480 Cow
    • Entrez Gene: 293 Human
    • Omim: 300151 Human
    • Omim: 403000 Human
    • SwissProt: P32007 Cow
    • SwissProt: P12236 Human
    • Unigene: 350927 Human
    • Alternative names

      • AAC3 antibody
      • Adenine nucleotide translocator 3 antibody
      • ADP antibody
      • ADP ATP carrier protein 3 antibody
      • ADP ATP carrier protein isoform T2 antibody
      • ADP ATP carrier protein liver antibody
      • ADP/ATP translocase 3 antibody
      • ADP/ATP translocator of liver antibody
      • ADT3_HUMAN antibody
      • ANT 2 antibody
      • ANT 3 antibody
      • ANT antibody
      • ANT3 antibody
      • ANT3Y antibody
      • ATP carrier protein 3 antibody
      • ATP carrier protein antibody
      • CDABP0051 antibody
      • isoform T2 antibody
      • MGC17525 antibody
      • SLC25A6 antibody
      • Solute carrier family 25 (mitochondrial carrier adenine nucleotide translocator) member 6 antibody
      • Solute carrier family 25 member 6 antibody
      see all

    Images

    • Western blot - Anti-SLC25A6 antibody (ab154007)
      Western blot - Anti-SLC25A6 antibody (ab154007)
      Anti-SLC25A6 antibody (ab154007) at 1/2000 dilution + 293T whole cell
      lysate at 30 µg

      Predicted band size: 33 kDa



      12% SDS PAGE
    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SLC25A6 antibody (ab154007)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SLC25A6 antibody (ab154007)
      Immunohistochemical analysis of paraffin embedded Cal27 xenograft labeling SLC25A6 with ab154007 antibody at 1/500.
    • Immunocytochemistry/ Immunofluorescence - Anti-SLC25A6 antibody (ab154007)
      Immunocytochemistry/ Immunofluorescence - Anti-SLC25A6 antibody (ab154007)
      Immunofluorescent analysis of methanol-fixed HeLa cells labeling SLC25A6 with ab154007 at 1/500 dilution. Lower panel costained with Hoechst 33342.

    Protocols

    • Immunohistochemistry protocols
    • Immunocytochemistry & immunofluorescence protocols
    • Western blot protocols

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download

    References (3)

    Publishing research using ab154007? Please let us know so that we can cite the reference in this datasheet.

    ab154007 has been referenced in 3 publications.

    • Kang Y  et al. Function of hTim8a in complex IV assembly in neuronal cells provides insight into pathomechanism underlying Mohr-Tranebjærg syndrome. Elife 8:N/A (2019). PubMed: 31682224
    • Kang Y  et al. Sengers Syndrome-Associated Mitochondrial Acylglycerol Kinase Is a Subunit of the Human TIM22 Protein Import Complex. Mol Cell 67:457-470.e5 (2017). PubMed: 28712726
    • Kang Y  et al. Tim29 is a novel subunit of the human TIM22 translocase and is involved in complex assembly and stability. Elife 5:N/A (2016). PubMed: 27554484

    Customer reviews and Q&As

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