Anti-SLC25A6 antibody (ab154007)
Key features and details
- Rabbit polyclonal to SLC25A6
- Suitable for: WB, IHC-P, ICC/IF
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-SLC25A6 antibody
See all SLC25A6 primary antibodies -
Description
Rabbit polyclonal to SLC25A6 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-P, ICC/IFmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Cow
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Immunogen
Recombinant fragment corresponding to a region within amino acids 1-298 of Human SLC25A6 (UniProt ID: P12236).
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Positive control
- 293T whole cell lysate, HeLa cells, Cal27 xenograft
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab154007 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 33 kDa.
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| IHC-P |
1/100 - 1/1000.
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| ICC/IF |
1/100 - 1/1000.
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| Notes |
|---|
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WB
1/500 - 1/3000. Predicted molecular weight: 33 kDa. |
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IHC-P
1/100 - 1/1000. |
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ICC/IF
1/100 - 1/1000. |
Target
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Function
Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis. -
Sequence similarities
Belongs to the mitochondrial carrier family.
Contains 3 Solcar repeats. -
Cellular localization
Mitochondrion inner membrane. The complex formed with ARL2BP, ARL2 and SLC25A6 is expressed in mitochondria. - Information by UniProt
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Database links
- Entrez Gene: 282480 Cow
- Entrez Gene: 293 Human
- Omim: 300151 Human
- Omim: 403000 Human
- SwissProt: P32007 Cow
- SwissProt: P12236 Human
- Unigene: 350927 Human
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Alternative names
- AAC3 antibody
- Adenine nucleotide translocator 3 antibody
- ADP antibody
see all
Images
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Western blot - Anti-SLC25A6 antibody (ab154007)Anti-SLC25A6 antibody (ab154007) at 1/2000 dilution + 293T whole cell
lysate at 30 µg
Predicted band size: 33 kDa
12% SDS PAGE -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SLC25A6 antibody (ab154007)Immunohistochemical analysis of paraffin embedded Cal27 xenograft labeling SLC25A6 with ab154007 antibody at 1/500. -
Immunocytochemistry/ Immunofluorescence - Anti-SLC25A6 antibody (ab154007)Immunofluorescent analysis of methanol-fixed HeLa cells labeling SLC25A6 with ab154007 at 1/500 dilution. Lower panel costained with Hoechst 33342.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab154007 has been referenced in 3 publications.
- Kang Y et al. Function of hTim8a in complex IV assembly in neuronal cells provides insight into pathomechanism underlying Mohr-Tranebjærg syndrome. Elife 8:N/A (2019). PubMed: 31682224
- Kang Y et al. Sengers Syndrome-Associated Mitochondrial Acylglycerol Kinase Is a Subunit of the Human TIM22 Protein Import Complex. Mol Cell 67:457-470.e5 (2017). PubMed: 28712726
- Kang Y et al. Tim29 is a novel subunit of the human TIM22 translocase and is involved in complex assembly and stability. Elife 5:N/A (2016). PubMed: 27554484