Overview

  • Product name

  • Description

    Rabbit polyclonal to SLC25A6
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, ICC/IF, WB, Flow Cytmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Cow
  • Immunogen

    Synthetic peptide within Human SLC25A6 aa 128-155 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    LCFVYPLDFARTRLAADVGKSGTEREFR


    Database link: P12236

  • Positive control

    • IHC-P: Human adipose tissue. ICC/IF: A549 cells. WB: A549 cell lysate. Flow Cyt: A549 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab230545 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/10 - 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
ICC/IF 1/10 - 1/50.
WB 1/1000. Predicted molecular weight: 33 kDa.
Flow Cyt 1/10 - 1/50.

Target

  • Function

    Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
  • Sequence similarities

    Belongs to the mitochondrial carrier family.
    Contains 3 Solcar repeats.
  • Cellular localization

    Mitochondrion inner membrane. The complex formed with ARL2BP, ARL2 and SLC25A6 is expressed in mitochondria.
  • Information by UniProt
  • Database links

  • Alternative names

    • AAC3 antibody
    • Adenine nucleotide translocator 3 antibody
    • ADP antibody
    • ADP ATP carrier protein 3 antibody
    • ADP ATP carrier protein isoform T2 antibody
    • ADP ATP carrier protein liver antibody
    • ADP/ATP translocase 3 antibody
    • ADP/ATP translocator of liver antibody
    • ADT3_HUMAN antibody
    • ANT 2 antibody
    • ANT 3 antibody
    • ANT antibody
    • ANT3 antibody
    • ANT3Y antibody
    • ATP carrier protein 3 antibody
    • ATP carrier protein antibody
    • CDABP0051 antibody
    • isoform T2 antibody
    • MGC17525 antibody
    • SLC25A6 antibody
    • Solute carrier family 25 (mitochondrial carrier adenine nucleotide translocator) member 6 antibody
    • Solute carrier family 25 member 6 antibody
    see all

Images

  • Anti-SLC25A6 antibody (ab230545) at 1/1000 dilution + A549 (human lung carcinoma cell line) cell lysates at 35 µg

    Developed using the ECL technique.

    Predicted band size: 33 kDa

  • Formalin-fixed, paraffin-embedded human adipose tissue stained for SLC25A6 with ab230545 at 1/10 dilution in immunohistochemical analysis.

  • A549 (Human lung carcinoma cell line) cells stained for SLC25A6 using ab230545 at a dilution of 1/10 in ICC/IF, followed by AlexaFluor® 488-conjugated goat anti-rabbit lgG (green).

    DAPI was used to stain the cell nucleus (blue).

  • Flow Cytometry analysis of A549 (Human lung carcinoma cell line) cells, labeling SLC25A6 with ab230545 at a 1/10 dilution (green) compared to a negative control (blue). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

References

ab230545 has not yet been referenced specifically in any publications.

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