Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferPreservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab108481 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500. Predicted molecular weight: 21 kDa.|
FunctionHigh-affinity, saturable copper transporter involved in dietary copper uptake.
Sequence similaritiesBelongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
modificationsO-Glycosylation at Thr-27 protects from proteolytic cleavage in the N-terminal extracellular domain.
Cellular localizationCell membrane. Localizes to the apical membrane in intestinal epithelial cells.
- Information by UniProt
- Copper transport 1 homolog antibody
- Copper transporter 1 antibody
- COPT1 antibody
This product has been referenced in:
- Wang Q et al. Gambogic acid reverses oxaliplatin resistance in colorectal cancer by increasing intracellular platinum levels. Oncol Lett 16:2366-2372 (2018). Read more (PubMed: 30008940) »
- Galluzzi L et al. Vitamin B6 metabolism influences the intracellular accumulation of cisplatin. Cell Cycle 12:417-21 (2013). Read more (PubMed: 23287530) »