Anti-SLC32A1/VGAT antibody (ab42939)
Key features and details
- Rabbit polyclonal to SLC32A1/VGAT
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
Overview
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Product name
Anti-SLC32A1/VGAT antibody
See all SLC32A1/VGAT primary antibodies -
Description
Rabbit polyclonal to SLC32A1/VGAT -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Rat
Predicted to work with: Mouse, Cow, Dog, Non human primates -
Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- Rat hippocampal lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.50
Constituents: 0.238% HEPES, 50% Glycerol, 0.87% Sodium chloride, 0.01% BSA -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab42939 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | (1) |
1/1000. Detects a band of approximately 53 kDa (predicted molecular weight: 58 kDa).
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Notes |
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WB
1/1000. Detects a band of approximately 53 kDa (predicted molecular weight: 58 kDa). |
Target
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Function
Involved in the uptake of GABA and glycine into the synaptic vesicles. -
Tissue specificity
Retina. Expressed throughout the horizontal cells or more specifically at the terminals. -
Sequence similarities
Belongs to the amino acid/polyamine transporter 2 family. -
Cellular localization
Cytoplasmic vesicle membrane. - Information by UniProt
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Database links
- Entrez Gene: 22348 Mouse
- Entrez Gene: 83612 Rat
- SwissProt: O35633 Mouse
- SwissProt: O35458 Rat
- Unigene: 143404 Mouse
- Unigene: 413854 Mouse
- Unigene: 10846 Rat
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Alternative names
- bA122O1.1 antibody
- GABA and glycine transporter antibody
- hVIAAT antibody
see all
Images
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Anti-SLC32A1/VGAT antibody (ab42939) at 1/1000 dilution + Rat hippocampal lysate at 20 µg
Secondary
Goat-anti-rabbit HRP. at 1/15000 dilution
Predicted band size: 58 kDa
Observed band size: 53 kDa why is the actual band size different from the predicted?
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab42939 has been referenced in 3 publications.
- Liang L et al. Involvement of homodomain interacting protein kinase 2-c-Jun N-terminal kinase/c-Jun cascade in the long-term synaptic toxicity and cognition impairment induced by neonatal Sevoflurane exposure. J Neurochem 154:372-388 (2020). PubMed: 31705656
- Lizarbe B et al. Neurochemical Modifications in the Hippocampus, Cortex and Hypothalamus of Mice Exposed to Long-Term High-Fat Diet. Front Neurosci 12:985 (2018). PubMed: 30670942
- Imbernon M et al. Hypothalamic KLF4 mediates leptin's effects on food intake via AgRP. Mol Metab 3:441-51 (2014). WB ; Rat . PubMed: 24944903