Overview

  • Product name

    Anti-SLC33A1/AT-1 antibody
    See all SLC33A1/AT-1 primary antibodies
  • Description

    Rabbit polyclonal to SLC33A1/AT-1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse
    Predicted to work with: Rat, Human
  • Immunogen

    Synthetic peptide within Human SLC33A1/AT-1 aa 500-549 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    G GSCVTALDGY YVESIICVFI GFGWWFFLGP KFKKLQDEGS SSWKCKRNN


    Database link: O00400

  • Positive control

    • Mouse heart lysate
  • General notes

    Protein previously labeled as SLC33A1.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituents: 50% Glycerol, 1% BSA
  • Concentration information loading...
  • Purity

    Protein A purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab213680 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/1000. Predicted molecular weight: 61 kDa.

Target

  • Function

    Probable acetyl-CoA transporter necessary for O-acetylation of gangliosides.
  • Tissue specificity

    Ubiquitous. Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. With strongest signals in pancreas.
  • Involvement in disease

    Spastic paraplegia autosomal dominant 42 (SPG42) [MIM:612539]: A form of spastic paraplegia, a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Rate of progression and the severity of symptoms are quite variable. Initial symptoms may include difficulty with balance, weakness and stiffness in the legs, muscle spasms, and dragging the toes when walking. In some forms of the disorder, bladder symptoms (such as incontinence) may appear, or the weakness and stiffness may spread to other parts of the body. Note=The disease is caused by mutations affecting the gene represented in this entry.
    Congenital cataracts, hearing loss, and neurodegeneration (CCHLND) [MIM:614482]: An autosomal recessive disorder characterized by congenital cataracts, severe psychomotor retardation, and hearing loss associated with decreased serum ceruloplasmin and copper. Brain MRI shows cerebral and cerebellar atrophy and hypomyelination. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Sequence similarities

    Belongs to the SLC33A transporter family.
  • Cellular localization

    Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • ACATN antibody
    • ACATN_HUMAN antibody
    • Acetyl CoA transporter antibody
    • Acetyl Coenzyme A transporter antibody
    • Acetyl coenzyme A transporter 1 antibody
    • Acetyl-CoA transporter 1 antibody
    • Acetyl-coenzyme A transporter 1 antibody
    • AT 1 antibody
    • AT-1 antibody
    • AT1 antibody
    • Human Angiotensin II Type 1 Receptor antibody
    • Slc33a1 antibody
    • Solute carrier family 33 (acetyl CoA transporter) member 1 antibody
    • Solute carrier family 33 member 1 antibody
    • spastic paraplegia 42 (autosomal dominant) antibody
    • SPG42 antibody
    see all

Images

  • Anti-SLC33A1/AT-1 antibody (ab213680) at 1/300 dilution + mouse heart lysate

    Secondary
    Goat Anti-Rabbit IgG Antibody (H+L), HRP Conjugated at 1/5000 dilution

    Predicted band size: 61 kDa

References

ab213680 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab213680.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up