Overview

  • Product name

  • Description

    Rabbit polyclonal to SLC35D1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    14 amino acid peptide near the N terminus of the Human SLC35D1

  • Positive control

    • A-20 lysate and Human Brain Cortex tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG

Applications

Our Abpromise guarantee covers the use of ab113717 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 39 kDa.
IHC-P Use a concentration of 5 µg/ml.

Target

  • Function

    Transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to into the endoplasmic reticulum lumen. May participate in glucuronidation and/or chondroitin sulfate biosynthesis.
  • Tissue specificity

    Ubiquitous.
  • Involvement in disease

    Defects in SLC35D1 are a cause of Schneckenbecken dysplasia (SCHBCKD) [MIM:269250]. Schneckenbecken dysplagia is a rare, autosomal recessive, lethal short-limbed skeletal dysplasia with platyspondylia.
  • Sequence similarities

    Belongs to the TPT transporter family. SLC35D subfamily.
  • Cellular localization

    Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • KIAA0260 antibody
    • MGC138236 antibody
    • S35D1_HUMAN antibody
    • SLC35D1 antibody
    • Solute carrier family 35 (UDP GlcA/UDP GalNAc transporter), member D1 antibody
    • Solute carrier family 35 (UDP glucuronic acid/UDP N acetylgalactosamine dual transporter), member D1 antibody
    • Solute carrier family 35 member D1 antibody
    • UDP galactose transporter related 7 antibody
    • UDP-galactose transporter-related protein 7 antibody
    • UDP-GlcA/UDP-GalNAc transporter antibody
    • UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter antibody
    • UGTrel7 antibody
    see all

Images

  • Immunohistochemical staining of Formalin-Fixed, Paraffin-Embedded Human Brain, Cortex using ab113717 at 5µg/ml
  • Lane 1 : Anti-SLC35D1 antibody (ab113717) at 1 µg/ml
    Lane 2 : Anti-SLC35D1 antibody (ab113717) at 2 µg/ml

    All lanes : A-20 lysate

    Predicted band size: 39 kDa

References

ab113717 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab113717.
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