Overview

  • Product name

    Anti-SLC35D2/HFRC antibody - C-terminal
  • Description

    Rabbit polyclonal to SLC35D2/HFRC - C-terminal
  • Host species

    Rabbit
  • Specificity

    At least two isoforms of SLC35D2/HFRC are known to exist; ab190170 will recognize both isoforms. ab190170 is predicted to not cross-react with SLC35D1 or SLC35D3.

  • Tested applications

    Suitable for: ICC, WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human SLC35D2/HFRC (C terminal). The peptide corresponds to 14 amino acids.
    Database link: Q76EJ3

  • Positive control

    • HeLa cell lysate; Human Small Intestine tissue; HeLa cells.
  • General notes

     This product was previously labelled as SLC35D2

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab190170 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC Use a concentration of 5 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 37 kDa.
IHC-P Use a concentration of 5 µg/ml.

Target

  • Function

    Antiporter transporting nucleotide sugars such as UDP-N-acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP-mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling.
  • Tissue specificity

    Highly expressed in heart, kidney, small intestine, placenta, lung and peripheral blood leukocyte. Weakly expressed in skeletal muscle and spleen. Not expressed in brain, colon and thymus.
  • Sequence similarities

    Belongs to the TPT transporter family. SLC35D subfamily.
  • Cellular localization

    Golgi apparatus membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Fringe connection antibody
    • HFRC 1 antibody
    • Hfrc antibody
    • HFRC1 antibody
    • Homolog of Fringe connection protein 1 antibody
    • MGC117215 antibody
    • MGC142139 antibody
    • Nucleotide sugar transporter UGTrel8 antibody
    • S35D2_HUMAN antibody
    • SLC35D2 antibody
    • Solute carrier family 35 member D2 antibody
    • SQV 7L antibody
    • SQV7-like protein antibody
    • SQV7L antibody
    • UDP N acetylglucosamine transporter antibody
    • UDP-galactose transporter-related protein 8 antibody
    • UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter antibody
    • UGTrel 8 antibody
    • UGTrel8 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human Small Intestine tissue labeling SLC35D2/HFRC with ab190170 at 5 µg/ml.

  • mmunocytochemistry of HeLa cells labeling SLC35D2/HFRC with ab190170 at 5 µg/ml.

  • Lane 1 : Anti-SLC35D2/HFRC antibody - C-terminal (ab190170) at 1 µg/ml
    Lane 2 : Anti-SLC35D2/HFRC antibody - C-terminal (ab190170) at 2 µg/ml

    All lanes : HeLa cell lysate

    Predicted band size: 37 kDa

References

ab190170 has not yet been referenced specifically in any publications.

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