Anti-SLC38A3/SN1 antibody (ab211516)
- Datasheet
- References (1)
- Protocols
Overview
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Product name
Anti-SLC38A3/SN1 antibody
See all SLC38A3/SN1 primary antibodies -
Description
Rabbit polyclonal to SLC38A3/SN1 -
Host species
Rabbit -
Tested applications
Suitable for: WB, Flow Cyt, IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide within Human SLC38A3/SN1 aa 442-468 (internal sequence) conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
Database link: Q99624 -
Positive control
- Human kidney tissue. HepG2 cells and cell line lysates.
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General notes
This product was previously labelled as SLC38A3
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.09% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
Purity
Ammonium Sulphate Precipitation -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
Applications
Our Abpromise guarantee covers the use of ab211516 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/1000. Predicted molecular weight: 56 kDa. | |
| Flow Cyt | 1/10 - 1/50. | |
| IHC-P | 1/50. |
Target
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Relevance
SLC38A3 is a sodium dependent amino acid/proton antiporter. It mediates electrogenic cotransport of glutamine and sodium ions in exchange for protons. It also recognizes histidine, asparagine and alanine. SLC38A3 may mediate amino acid transport in either direction under physiological conditions an may play a role in nitrogen metabolism and synaptic transmission. -
Cellular localization
Cell membrane; Multipass membrane protein -
Database links
- Entrez Gene: 10991 Human
- Omim: 604437 Human
- SwissProt: Q99624 Human
- Unigene: 76460 Human
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Alternative names
- G17 antibody
- N system amino acid transporter 1 antibody
- N-system amino acid transporter 1 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SLC38A3/SN1 antibody (ab211516)Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human kidney tissue labeling SLC38A3/SN1 with ab211516 at 1/50 dilution.
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Western blot - Anti-SLC38A3/SN1 antibody (ab211516)Anti-SLC38A3/SN1 antibody (ab211516) at 1/1000 dilution + HepG2 cell line lysates at 35 µg
Predicted band size: 56 kDa -
Flow Cytometry - Anti-SLC38A3/SN1 antibody (ab211516)Flow cytometric analysis of HepG2 cells labeling SLC38A3/SN1 with ab211516 at 1/10 dilution (lower histogram) compared to a negative control cell (upper histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Datasheets and documents
References
This product has been referenced in:
- Baek JH et al. Glutamine Supplementation Ameliorates Chronic Stress-induced Reductions in Glutamate and Glutamine Transporters in the Mouse Prefrontal Cortex. Exp Neurobiol 28:270-278 (2019). Read more (PubMed: 31138994) »
