Anti-ZIP-5 antibody (ab105194)
Key features and details
- Rabbit polyclonal to ZIP-5
- Suitable for: ICC/IF, WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-ZIP-5 antibody -
Description
Rabbit polyclonal to ZIP-5 -
Host species
Rabbit -
Specificity
ab105194 is predicted not to cross-react with other ZIP family members. -
Tested applications
Suitable for: ICC/IF, WB, IHC-Pmore details -
Species reactivity
Reacts with: Mouse, Human -
Immunogen
Synthetic peptide corresponding to Human ZIP-5 (internal sequence).
Database link: NP_001128667 -
Positive control
- Human spleen tissue lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab105194 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
ICC/IF |
Use a concentration of 20 µg/ml.
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WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 56 kDa.
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IHC-P |
Use at an assay dependent concentration.
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Notes |
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ICC/IF
Use a concentration of 20 µg/ml. |
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 56 kDa. |
IHC-P
Use at an assay dependent concentration. |
Target
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Function
May play a role in polarized cells by carrying out serosal-to-mucosal zinc transport. Plays a role in eye development. Could regulate the BMP/TGF-beta (bone morphogenetic protein/transforming growth factor-beta) signaling pathway and modulates extracellular matrix (ECM) proteins of the sclera (PubMed:24891338). Seems to play a central role in controlling organismal zinc status. -
Tissue specificity
Expressed in liver, kidney, pancreas, small intestine, colon, spleen, fetal liver and fetal kidney. -
Involvement in disease
Myopia 24, autosomal dominant -
Sequence similarities
Belongs to the ZIP transporter (TC 2.A.5) family. -
Post-translational
modificationsGlycosylated. -
Cellular localization
Basolateral cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 283375 Human
- Entrez Gene: 72002 Mouse
- GenBank: NM_173596 Human
- Omim: 608730 Human
- SwissProt: Q6ZMH5 Human
- SwissProt: Q9D856 Mouse
- Unigene: 591018 Human
- Unigene: 22983 Mouse
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Alternative names
- LZT Hs7 antibody
- MGC34778 antibody
- OTTHUMP00000211153 antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab105194 has not yet been referenced specifically in any publications.