Overview

  • Product name

    Anti-SLC3A1 antibody
  • Description

    Rabbit polyclonal to SLC3A1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant fragment corresponding to Human SLC3A1 (C terminal).
    Database link: Q07837

  • Positive control

    • HT-29, HepG2, 293T, BXPC-3, PC12 and mouse liver lysates. HeLa cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab196552 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200.
WB 1/500 - 1/2000. Predicted molecular weight: 79 kDa.
ICC/IF 1/50 - 1/200.

Target

  • Function

    Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system B(0,+)-like activity). May function as an activator of SLC7A9 and be involved in the high-affinity reabsorption of cystine in the kidney tubule.
  • Tissue specificity

    Expressed in the brush border membrane in the kidney (at protein level). Predominantly expressed in the kidney, small intestine and pancreas. Weakly expressed in liver.
  • Involvement in disease

    Cystinuria
    Hypotonia-cystinuria syndrome
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • +)-type amino acid transport protein antibody
    • amino acid transporter 1 antibody
    • ATR1 antibody
    • B(0 antibody
    • B(0,+)-type amino acid transport protein antibody
    • CSNU1 antibody
    • D2H antibody
    • FLJ34681 antibody
    • NBAT antibody
    • Neutral and basic amino acid transport protein rBAT antibody
    • RBAT antibody
    • SLC31_HUMAN antibody
    • SLC3A1 antibody
    • SLC3A1 variant B antibody
    • SLC3A1 variant C antibody
    • SLC3A1 variant D antibody
    • SLC3A1 variant E antibody
    • SLC3A1 variant F antibody
    • SLC3A1 variant G antibody
    • solute carrier family 3 (cystine, dibasic and neutral amino acid transporters), member 1 antibody
    • Solute carrier family 3 member 1 antibody
    see all

Images

  • All lanes : Anti-SLC3A1 antibody (ab196552) at 1/500 dilution

    Lane 1 : HT-29 extract
    Lane 2 : HepG2 extract
    Lane 3 : 293T extract
    Lane 4 : BXPC-3 extract
    Lane 5 : PC12 extract
    Lane 6 : Mouse liver extract

    Predicted band size: 79 kDa

  • Immunofluorescence analysis of HeLa cells labeling SLC3A1 using ab196552, at 1/50 dilution. Lower panel shows DAPI for nuclear staining (Blue).

References

ab196552 has not yet been referenced specifically in any publications.

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