Product nameAnti-SLC40A1 antibody
See all SLC40A1 primary antibodies
DescriptionRabbit polyclonal to SLC40A1
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Synthetic peptide. This information is considered to be commercially sensitive.
- WB: CACO2 whole cell lysate.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.01% Sodium azide
Concentration information loading...
Our Abpromise guarantee covers the use of ab235166 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 5 µg/ml. Predicted molecular weight: 63 kDa.|
FunctionMay be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin).
Tissue specificityExpressed in placenta, intestine, muscle and spleen.
Involvement in diseaseDefects in SLC40A1 are the cause of hemochromatosis type 4 (HFE4) [MIM:606069]. HFE4 is an autosomal dominant iron-loading disorder characterized by early iron accumulation in reticuloendothelial cells and a marked increase in serum ferritin before elevation of the transferrin saturation.
Sequence similaritiesBelongs to the SLC40A transporter family.
Cellular localizationCell membrane. Localized to the basolateral membrane of polarized epithelial cells.
- Information by UniProt
- Ferroportin 1 antibody
- Ferroportin antibody
- Ferroportin-1 antibody
All lanes : Anti-SLC40A1 antibody (ab235166) at 5 µg/ml
Lane 1 : CACO2 (Human colorectal adenocarcinoma cell line) whole cell lysate
Lane 2 : K562 (Human chronic myelogenous leukemia cell line from bone marrow ) whole cell lysate
Lane 3 : HepG2 (Human liver hepatocellular carcinoma cell line) whole cell lysate
Lane 4 : MCF7 (Human breast adenocarcinoma cell line) whole cell lysate
Lysates/proteins at 35 µg per lane.
All lanes : Goat anti-Rabbit IgG [H&L] HRP at 1/70000 dilution
Predicted band size: 63 kDa
Exposure time: 40 seconds
ab235166 has not yet been referenced specifically in any publications.