Overview

  • Product name

  • Description

    Goat polyclonal to SLC47A2
  • Host species

    Goat
  • Specificity

    This antibody is expected to recognize both reported isoforms (NP_690872.2; NP_001093116.1).
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide:

    SECHVDFFRTPEEAH,

    (with a Cysteine residue linker), corresponding to C terminal amino acids 546-560 of Human SLC47A2 (NP_690872.2; NP_001093116.1).

  • Positive control

    • Human testis lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab128823 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 1 µg/ml. Predicted molecular weight: 65 kDa.

Target

  • Function

    Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Responsible for the secretion of cationic drugs across the brush border membranes.
  • Tissue specificity

    Isoform 3 is predominantly expressed in kidney. Isoform 6 is expressed in brain.
  • Sequence similarities

    Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
  • Cellular localization

    Cell membrane. Localized at the brush border membranes of the proximal tubules.
  • Information by UniProt
  • Database links

  • Alternative names

    • H(+)/organic cation antiporter kidney-specific antibody
    • H+/organic cation antiporter antibody
    • hMATE-2 antibody
    • Kidney-specific H(+)/organic cation antiporter antibody
    • MATE-2 antibody
    • MATE2 B antibody
    • MATE2 K antibody
    • MATE2K antibody
    • Multidrug and toxin extrusion 2 antibody
    • Multidrug and toxin extrusion protein 2 antibody
    • S47A2_HUMAN antibody
    • SLC47A2 antibody
    • Solute carrier family 47 member 2 antibody
    see all

Images

  • Anti-SLC47A2 antibody (ab128823) at 0.3 µg/ml (incubation time: 1 hour) + Human testis lysates in RIPA buffer at 35 µg

    Predicted band size: 65 kDa

References

ab128823 has not yet been referenced specifically in any publications.

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