Overview

  • Product name
    Anti-SLC47A2 antibody - N-terminal
    See all SLC47A2 primary antibodies
  • Description
    Rabbit polyclonal to SLC47A2 - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human SLC47A2 aa 132-161 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q86VL8

  • Positive control
    • Mouse kidney tissue and A2058 cell line lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab174344 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 65 kDa.

Target

  • Function
    Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Responsible for the secretion of cationic drugs across the brush border membranes.
  • Tissue specificity
    Isoform 3 is predominantly expressed in kidney. Isoform 6 is expressed in brain.
  • Sequence similarities
    Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
  • Cellular localization
    Cell membrane. Localized at the brush border membranes of the proximal tubules.
  • Information by UniProt
  • Database links
  • Alternative names
    • H(+)/organic cation antiporter kidney-specific antibody
    • H+/organic cation antiporter antibody
    • hMATE-2 antibody
    • Kidney-specific H(+)/organic cation antiporter antibody
    • MATE-2 antibody
    • MATE2 B antibody
    • MATE2 K antibody
    • MATE2K antibody
    • Multidrug and toxin extrusion 2 antibody
    • Multidrug and toxin extrusion protein 2 antibody
    • S47A2_HUMAN antibody
    • SLC47A2 antibody
    • Solute carrier family 47 member 2 antibody
    see all

Images

  • All lanes : Anti-SLC47A2 antibody - N-terminal (ab174344) at 1/100 dilution

    Lane 1 : Mouse kidney tissue lysate
    Lane 2 : A2058 cell line lysate

    Lysates/proteins at 35 µg per lane.

    Predicted band size: 65 kDa

References

This product has been referenced in:
  • He R  et al. Different effect of testosterone and oestrogen on urinary excretion of metformin via regulating OCTs and MATEs expression in the kidney of mice. J Cell Mol Med 20:2309-2317 (2016). WB . Read more (PubMed: 27469532) »
See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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