The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-SLC47A2 antibody (ab106117)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
H(+)/organic cation antiporter kidney-specific
H+/organic cation antiporter
Kidney-specific H(+)/organic cation antiporter
Multidrug and toxin extrusion 2
Multidrug and toxin extrusion protein 2
Solute carrier family 47 member 2
Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Responsible for the secretion of cationic drugs across the brush border membranes.
Isoform 3 is predominantly expressed in kidney. Isoform 6 is expressed in brain.
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
Cell membrane. Localized at the brush border membranes of the proximal tubules.