Overview

  • Product name

    Anti-SLC5A11 antibody
  • Description

    Rabbit polyclonal to SLC5A11
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other Human proteins.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Chimpanzee, Monkey, Gorilla, Common marmoset, Orangutan
  • Immunogen

    Synthetic 16 amino acid peptide from an internal region of Human SLC5A11 (NP_443176.2)

  • Positive control

    • Human liver and Human kidney.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C.
  • Storage buffer

    Preservative: 0.1% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab140942 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function

    Involved in the sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Also can transport D-chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D-xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney.
  • Tissue specificity

    Highest expression in heart, skeletal muscle, kidney, liver and placenta. Weaker expression in brain, colon, spleen, lung and peripheral blood leukocytes.
  • Sequence similarities

    Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Form

    There are 4 isoforms produced by alternative splicing.
  • Alternative names

    • homolog of rabbit KST1 antibody
    • KST1 antibody
    • Na(+)/myo-inositol cotransporter 2 antibody
    • na+/myo-inositol cotransporter 2 antibody
    • putative sodium-coupled cotransporter RKST1 antibody
    • RKST1 antibody
    • SC5AB_HUMAN antibody
    • SGLT6 antibody
    • SLC5A11 antibody
    • SMIT2 antibody
    • Sodium-dependent glucose cotransporter antibody
    • Sodium/glucose cotransporter KST1 antibody
    • Sodium/myo-inositol cotransporter 2 antibody
    • Sodium/myo-inositol transporter 2 antibody
    • solute carrier family 5 (sodium/glucose cotransporter), member 11 antibody
    • Solute carrier family 5 member 11 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human liver tissue labelling SLC5A11 with ab140942 at 10 µg/ml.
  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human kidney tissue labelling SLC5A11 with ab140942 at 10 µg/ml.

References

ab140942 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab140942.
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